Browsing by Author "Du, Rose"
Now showing items 1-12 of 12
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Analysis of Morphological Parameters to Differentiate Rupture Status in Anterior Communicating Artery Aneurysms
Lin, Ning; Ho, Allen; Charoenvimolphan, Nareerat; Frerichs, Kai U.; Day, Arthur L.; Du, Rose (Public Library of Science, 2013)In contrast to size, the association of morphological characteristics of intracranial aneurysms with rupture has not been established in a systematic manner. We present an analysis of the morphological variables that are ... -
The Association between Meteorological Parameters and Aneurysmal Subarachnoid Hemorrhage: A Nationwide Analysis
Lai, Pui Man Rosalind; Dasenbrock, Hormuzdiyar; Du, Rose (Public Library of Science, 2014)Prior research has suggested that regional weather patterns impact the risk of rupture of cerebral aneurysms, but the findings in the literature have been inconsistent. Furthermore, no nationwide analysis to date has ... -
Association between S100B Levels and Long-Term Outcome after Aneurysmal Subarachnoid Hemorrhage: Systematic Review and Pooled Analysis
Lai, Pui Man Rosalind; Du, Rose (Public Library of Science, 2016)S100 calcium binding protein B (S100B), a well-studied marker for neurologic injury, has been suggested as a candidate for predicting outcome after subarachnoid hemorrhage. We performed a pooled analysis summarizing the ... -
Brain temperature and its fundamental properties: a review for clinical neuroscientists
Wang, Huan; Wang, Bonnie; Normoyle, Kieran P.; Jackson, Kevin; Spitler, Kevin; Sharrock, Matthew F.; Miller, Claire M.; Best, Catherine; Llano, Daniel; Du, Rose (Frontiers Media S.A., 2014)Brain temperature, as an independent therapeutic target variable, has received increasingly intense clinical attention. To date, brain hypothermia represents the most potent neuroprotectant in laboratory studies. Although ... -
Combination inhibition of PI3K and mTORC1 yields durable remissions in orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases
Ni, Jing; Ramkissoon, Shakti H.; Xie, Shaozhen; Goel, Shom; Stover, Daniel G.; Guo, Hanbing; Luu, Victor; Marco, Eugenio; Ramkissoon, Lori A.; Kang, Yun Jee; Hayashi, Marika; Nguyen, Quang-De; Ligon, Azra H.; Du, Rose; Claus, Elizabeth B.; Alexander, Brian M.; Yuan, Guo-Cheng; Wang, Zhigang C.; Iglehart, J. Dirk; Krop, Ian E.; Roberts, Thomas M.; Winer, Eric P.; Lin, Nancy U.; Ligon, Keith L.; Zhao, Jean J. (2016)Brain metastases represent the greatest clinical challenge in treating HER2-positive breast cancer. We report the development of orthotopic patient-derived xenografts (PDXs) of HER2-expressing breast cancer brain metastases ... -
Genome-wide association study reveals class I MHC–restricted T cell–associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations
Du, Rose; Litonjua, Augusto Ampil; Tantisira, Kelan; Lasky-Su, Jessica A. Lasky; Sunyaev, Shamil R.; Klanderman, Barbara; Celedón, Juan C.; Avila, Lydiana; Soto-Quiros, Manuel E.; Weiss, Scott Tillman (Elsevier BV, 2012)Background— It has recently been shown that vitamin D deficiency can increase asthma development and severity and that variations in vitamin D receptor genes are associated with asthma susceptibility. Objective— We sought ... -
Hemodynamic Impact of a Spontaneous Cervical Dissection on an Ipsilateral Saccular Aneurysm
See, Alfred P.; Gross, Bradley A.; Penn, David L.; Du, Rose; Frerichs, Kai U (Korean Society of Cerebrovascular Surgeons; Society of Korean Endovascular Neurosurgeons, 2016)The dynamic, hemodynamic impact of a cervical dissection on an ipsilateral, intracranial saccular aneurysm has not been well illustrated. This 45-year-old female was found to have a small, supraclinoid aneurysm ipsilateral ... -
The Impact of Insurance Status on the Outcomes after Aneurysmal Subarachnoid Hemorrhage
Lai, Pui Man Rosalind; Dasenbrock, Hormuzdiyar; Lin, Ning; Du, Rose (Public Library of Science, 2013)Investigation into the association of insurance status with the outcomes of patients undergoing neurosurgical intervention has been limited: this is the first nationwide study to analyze the impact of primary payer on the ... -
Morphological Parameters Associated with Ruptured Posterior Communicating Aneurysms
Ho, Allen; Lin, Ning; Charoenvimolphan, Nareerat; Stanley, Mary; Frerichs, Kai U.; Day, Arthur L.; Du, Rose (Public Library of Science, 2014)The rupture risk of unruptured intracranial aneurysms is known to be dependent on the size of the aneurysm. However, the association of morphological characteristics with ruptured aneurysms has not been established in a ... -
Platform dependence of inference on gene-wise and gene-set involvement in human lung development
Bhattacharya, Soumyaroop; Metje, Stephanie; Gaedigk, Roger; Mariani, Thomas J; Leeder, J Steven; Du, Rose; Tantisira, Kelan; Carey, Vincent James; Kho, Alvin Thong-Juak; Klanderman, Barbara Jordan; Lazarus, Ross; Weiss, Scott Tillman (BioMed Central, 2009)Background: With the recent development of microarray technologies, the comparability of gene expression data obtained from different platforms poses an important problem. We evaluated two widely used platforms, Affymetrix ... -
Posterior Cerebral Artery Angle and the Rupture of Basilar Tip Aneurysms
Ho, Allen L.; Mouminah, Amr; Du, Rose (Public Library of Science, 2014)Since the initial publication of the International Study of Unruptured Intracranial Aneurysms (ISUIA), management of unruptured intracranial aneurysms has been mainly based on the size of the aneurysm. The contribution of ... -
What Sequences on High-Field MR Best Depict Temporal Resolution of Experimental ICH and Edema Formation in Mice?
Li, Mingchang; Akhavan-Sharif, Reza M.; Friedlander, Robert M.; Du, Rose; Thiex, Ruth (Hindawi Publishing Corporation, 2012)Background and Purpose: Pilot study to examine the use of T1-, T2-, and T2*-weighted images for evaluating hematoma size and extent of edema in mouse brain at high field. Methods: Following collagenase-induced intracerebral ...