Now showing items 1-10 of 10

    • In Vivo Brillouin Analysis of the Aging Crystalline Lens 

      Besner, Sebastien; Scarcelli, Giuliano; Pineda, Roberto; Yun, Seok-Hyun (The Association for Research in Vision and Ophthalmology, 2016)
      Purpose To analyze the age dependence of the longitudinal modulus of the crystalline lens in vivo using Brillouin scattering data in healthy subjects. Methods: Brillouin scans were performed along the crystalline lens in ...
    • In vivo Brillouin optical microscopy of the human eye 

      Scarcelli, Giuliano; Yun, Seok-Hyun (Optical Society of America, 2012)
      We report the first Brillouin measurement of the human eye in vivo. We constructed a Brillouin optical scanner safe for human use by employing continuous-wave laser light at 780 nm at a low power of 0.7 mW. With a single ...
    • Line-scanning Brillouin microscopy for rapid non-invasive mechanical imaging 

      Zhang, Jitao; Fiore, Antonio; Yun, Seok-Hyun; Kim, Hanyoup; Scarcelli, Giuliano (Nature Publishing Group, 2016)
      Brillouin spectroscopy probes the mechanical properties of material by measuring the optical frequency shift induced by photon-phonon scattering interactions. In traditional configurations, Brillouin spectrometers measure ...
    • Multistage VIPA etalons for high-extinction parallel Brillouin spectroscopy 

      Scarcelli, Giuliano; Yun, Seok-Hyun (Optical Society of America, 2011)
      We demonstrate a high-resolution high-extinction parallel spectrometer for Brillouin spectroscopy of turbid samples. Cascading multiple VIPA etalons in the cross-axis configuration allowed us to achieve a high extinction ...
    • A Novel Laser Vaccine Adjuvant Increases the Motility of Antigen Presenting Cells 

      Chen, Xinyuan; Kim, Pilhan; Farinelli, Bill; Doukas, Apostolos; Yun, Seok-Hyun; Gelfand, Jeffrey Alan; Anderson, Richard Rox; Wu, Mei X. (Public Library of Science, 2010)
      Background: Development of a potent vaccine adjuvant without introduction of any side effects remains an unmet challenge in the field of the vaccine research. Methodology/Principal Findings: We found that laser at a specific ...
    • Numerical model of optical coherence tomographic vibrography imaging to estimate corneal biomechanical properties 

      Kling, Sabine; Akca, Imran B.; Chang, Ernest W.; Scarcelli, Giuliano; Bekesi, Nandor; Yun, Seok-Hyun; Marcos, Susana (The Royal Society, 2014)
      Most techniques measuring corneal biomechanics in vivo are biased by side factors. We demonstrate the ability of optical coherence tomographic (OCT) vibrography to determine corneal material parameters, while reducing ...
    • On the near-wall accumulation of injectable particles in the microcirculation: smaller is not better 

      Lee, Tae-Rin; Choi, Myunghwan; Kopacz, Adrian M.; Yun, Seok-Hyun; Liu, Wing Kam; Decuzzi, Paolo (Nature Publishing Group, 2013)
      Although most nanofabrication techniques can control nano/micro particle (NMP) size over a wide range, the majority of NMPs for biomedical applications exhibits a diameter of ~100 nm. Here, the vascular distribution of ...
    • Parametric Simulations of Slanted 1D Photonic Crystal Sensors 

      Breuer-Weil, Aaron; Almasoud, Naif Nasser; Abbasi, Badaruddin; Yetisen, Ali K.; Yun, Seok-Hyun; Butt, Haider (Springer US, 2016)
      Photonic crystals and band gap materials act as manipulators of light and have a plethora of applications. They are made up of stacks of alternating dielectric constants. This article shows the simulations of an inclined, ...
    • Reconfigurable optical assembly of nanostructures 

      Montelongo, Yunuen; Yetisen, Ali K.; Butt, Haider; Yun, Seok-Hyun (Nature Publishing Group, 2016)
      Arrangements of nanostructures in well-defined patterns are the basis of photonic crystals, metamaterials and holograms. Furthermore, rewritable optical materials can be achieved by dynamically manipulating nanoassemblies. ...
    • Two-photon excited photoconversion of cyanine-based dyes 

      Kwok, Sheldon J. J.; Choi, Myunghwan; Bhayana, Brijesh; Zhang, Xueli; Ran, Chongzhao; Yun, Seok-Hyun (Nature Publishing Group, 2016)
      The advent of phototransformable fluorescent proteins has led to significant advances in optical imaging, including the unambiguous tracking of cells over large spatiotemporal scales. However, these proteins typically ...