Now showing items 1-2 of 2

    • Small Molecule Control of Virulence Gene Expression in Francisella tularensis 

      Charity, James Carl; Blalock, LeeAnn T.; Costante-Hamm, Michelle M.; Kasper, Dennis Lee; Dove, Simon L. (Public Library of Science, 2009)
      In Francisella tularensis, the SspA protein family members MglA and SspA form a complex that associates with RNA polymerase (RNAP) to positively control the expression of virulence genes critical for the intramacrophage ...
    • Twin RNA Polymerase–associated Proteins Control Virulence Gene Expression in Francisella tularensis 

      Costante-Hamm, Michelle M; Balon, Emmy; Schneewind, Olaf; Charity, James Carl; Rubin, Eric Joseph; Boyd, Dana H.; Dove, Simon L. (Public Library of Science, 2007)
      The MglA protein is the only known regulator of virulence gene expression in Francisella tularensis, yet it is unclear how it functions. F. tularensis also contains an MglA-like protein called SspA. Here, we show that MglA ...