Now showing items 1-4 of 4

    • Biosensor Platforms for Molecular Analyses of Circulating Cancer Biomarkers 

      Shao, Huilin (2013-10-15)
      Solid cancers often shed (sub)cellular materials into the circulation, such as circulating tumor cells and extracellular microvesicles. Mounting evidence supports that these circulating materials could serve as surrogate ...
    • Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma 

      Shao, Huilin; Chung, Jaehoon; Lee, Kyungheon; Balaj, Leonora; Min, Changwook; Carter, Bob S.; Hochberg, Fred H.; Breakefield, Xandra O.; Lee, Hakho; Weissleder, Ralph (Nature Pub. Group, 2015)
      Real-time monitoring of drug efficacy in glioblastoma multiforme (GBM) is a major clinical problem as serial re-biopsy of primary tumours is often not a clinical option. MGMT (O6-methylguanine DNA methyltransferase) and ...
    • Diagnostic technologies for circulating tumour cells and exosomes 

      Shao, Huilin; Chung, Jaehoon; Issadore, David (Portland Press Ltd., 2016)
      Circulating tumour cells (CTCs) and exosomes are promising circulating biomarkers. They exist in easily accessible blood and carry large diversity of molecular information. As such, they can be easily and repeatedly obtained ...
    • Magnetic Nanoparticles and MicroNMR for Diagnostic Applications 

      Shao, Huilin; Min, Changwook; Issadore, David Aaron; Liong, Monty; Yoon, Tae-Jong; Weissleder, Ralph; Lee, Hakho (Ivyspring International Publisher, 2012)
      Sensitive and quantitative measurements of clinically relevant protein biomarkers, pathogens and cells in biological samples would be invaluable for disease diagnosis, monitoring of malignancy, and for evaluating therapy ...