Browsing by Author "Spencer, Joel A."

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    • Direct measurement of local oxygen concentration in the bone marrow of live animals 

      Spencer, Joel A.; Ferraro, Francesca; Roussakis, Emmanuel; Klein, Alyssa; Wu, Juwell; Runnels, Judith M.; Zaher, Walid; Mortensen, Luke J.; Alt, Clemens; Turcotte, Raphaël; Yusuf, Rushdia; Côté, Daniel; Vinogradov, Sergei A.; Scadden, David T.; Lin, Charles P. (2014)
      Characterizing how the microenvironment, or niche, regulates stem cell activity is central to understanding stem cell biology and to developing strategies for therapeutic manipulation of stem cells1. Low oxygen tension ...

    • Two-Photon Antenna-Core Oxygen Probe with Enhanced Performance 

      Roussakis, Emmanuel; Spencer, Joel A.; Lin, Charles P.; Vinogradov, Sergei A. (American Chemical Society, 2014)
      Recent development of two-photon phosphorescence lifetime microscopy (2PLM) of oxygen enabled first noninvasive high-resolution measurements of tissue oxygenation in vivo in 3D, providing valuable physiological information. ...