Browsing by Author "Liu, Yibin"
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Elimination of unaltered DNA in mixed clinical samples via nuclease-assisted minor-allele enrichment
Song, Chen; Liu, Yibin; Fontana, Rachel; Makrigiorgos, Alexander; Mamon, Harvey; Kulke, Matthew H.; Makrigiorgos, G. Mike (Oxford University Press, 2016)Presence of excess unaltered, wild-type (WT) DNA providing no information of biological or clinical value often masks rare alterations containing diagnostic or therapeutic clues in cancer, prenatal diagnosis, infectious ...