Browsing by Author "Tschumperlin, Daniel J."

Now showing items 1-3 of 3

    • Cell Elasticity Determines Macrophage Function 

      Patel, Naimish R.; Bole, Medhavi; Chen, Cheng; Hardin, Charles Corey; Kho, Alvin Thong-Juak; Mih, Justin; Deng, Linhong; Butler, James Preston; Tschumperlin, Daniel J.; Fredberg, Jeffrey J.; Krishnan, Ramaswamy; Koziel, Henryk (Public Library of Science, 2012)
      Macrophages serve to maintain organ homeostasis in response to challenges from injury, inflammation, malignancy, particulate exposure, or infection. Until now, receptor ligation has been understood as being the central ...

    • Matrix Rigidity Regulates Cancer Cell Growth by Modulating Cellular Metabolism and Protein Synthesis 

      Tilghman, Robert W.; Blais, Edik M.; Cowan, Catharine R.; Sherman, Nicholas E.; Grigera, Pablo R.; Jeffery, Erin D.; Fox, Jay W.; Blackman, Brett R.; Tschumperlin, Daniel J.; Papin, Jason A.; Parsons, J. Thomas (Public Library of Science, 2012)
      Background: Tumor cells in vivo encounter diverse types of microenvironments both at the site of the primary tumor and at sites of distant metastases. Understanding how the various mechanical properties of these microenvironments ...

    • Unjamming and cell shape in the asthmatic airway epithelium 

      Park, Jin-Ah; Kim, Jae Hun; Bi, Dapeng; Mitchel, Jennifer; Qazvini, Nader Taheri; Tantisira, Kelan; Park, Chan Young Young; McGill, Maureen P; Kim, Sae-Hoon; Gweon, Bomi; Notbohm, Jacob K; Steward Jr, Robert; Burger, Stephanie; Randell, Scott H.; Kho, Alvin Thong-Juak; Tambe, Dhananjay; Hardin, Corey; Shore, Stephanie Ann; Israel, Elliot; Weitz, David A.; Tschumperlin, Daniel; Henske, Elizabeth Petri; Weiss, Scott Tillman; Manning, Mary Ellen; Butler, James P.; Drazen, Jeffrey Mark; Fredberg, Jeffrey J. (Nature Publishing Group, 2015)
      From coffee beans flowing in a chute to cells remodelling in a living tissue, a wide variety of close-packed collective systems— both inert and living—have the potential to jam. The collective can sometimes flow like a ...