Now showing items 1-11 of 11

    • Co-Registered Spectrally Encoded Confocal Microscopy and Optical Frequency Domain Imaging System 

      Kang, D.K.; Suter, Melissa; Boudoux, Caroline; Yachimski, P.S.; Puricelli, W.P.; Nishioka, Norman Shizuaki; Mino-Kenudson, Mari; Lauwers, Gregory Y.; Bouma, Brett; Tearney, Guillermo James (Wiley-Blackwell, 2010)
      Spectrally encoded confocal microscopy and optical frequency domain imaging are two non-contact optical imaging technologies that provide images of tissue cellular and architectural morphology, which are both used for ...
    • Comprehensive confocal endomicroscopy of the esophagus in vivo 

      Kang, Dongkyun; Schlachter, Simon C.; Carruth, Robert W.; Kim, Minkyu; Wu, Tao; Tabatabaei, Nima; Vacas-Jacques, Paulino; Shishkov, Milen; Woods, Kevin; Sauk, Jenny S.; Leung, John; Nishioka, Norman S.; Tearney, Guillermo J. (© Georg Thieme Verlag KG, 2014)
      Background and study aims: Biopsy sampling error can be a problem for the diagnosis of certain gastrointestinal tract diseases. Spectrally-encoded confocal microscopy (SECM) is a high-speed reflectance confocal microscopy ...
    • Comprehensive Imaging of Gastroesophageal Biopsy Samples by Spectrally Encoded Confocal Microscopy 

      Kang, DongKyun; Suter, Melissa; Boudoux, Caroline; Yoo, Hongki; Yachimski, Patrick S.; Puricelli, William P.; Nishioka, Norman Shizuaki; Mino-Kenudson, Mari; Lauwers, Gregory Y.; Bouma, Brett; Tearney, Guillermo James (Elsevier BV, 2010)
      Background: Spectrally encoded confocal microscopy (SECM) is a high-speed reflectance confocal microscopy technique that has the potential to be used for acquiring comprehensive images of the entire distal esophagus ...
    • Comprehensive Microscopy of the Esophagus in Human Patients with Optical Frequency Domain Imaging 

      Suter, Melissa; Vakoc, Benjamin; Yachimski, Patrick S.; Shishkov, Milen Stefanov; Lauwers, Gregory Y.; Mino-Kenudson, Mari; Bouma, Brett; Nishioka, Norman Shizuaki; Tearney, Guillermo James (Elsevier BV, 2008)
      Background: Optical coherence tomography (OCT) is a cross-sectional, high-resolution imaging modality that has been shown to accurately differentiate esophageal specialized intestinal metaplasia (SIM) from gastric cardia ...
    • Cyclooxygenase-2 expression in esophageal epithelium before and after photodynamic therapy for Barrett’s esophagus with high-grade dysplasia or intramucosal carcinoma 

      Yachimski, Patrick; Mino-Kenudson, Mari; Sherwood, Margaret E.; Puricelli, William P.; Nishioka, Norman Shizuaki; Lauwers, Gregory Y. (Springer Nature, 2011)
      Cyclooxygenase-2 expression is upregulated in Barrett’s esophagus and esophageal adenocarcinoma. Photodynamic therapy using porfimer sodium can result in ablation of dysplasia and intramucosal carcinoma, eradication of ...
    • Effect of Tumor Characteristics and Duplication of the Muscularis Mucosae on the Endoscopic Staging of Superficial Barrett Esophagus-related Neoplasia 

      Mandal, Rajni V.; Forcione, David G.; Brugge, William Robert; Nishioka, Norman Shizuaki; Mino-Kenudson, Mari; Lauwers, Gregory Y. (Ovid Technologies (Wolters Kluwer Health), 2009)
      Endoscopic mucosal resection (EMR) is being advocated as a diagnostic, staging, and therapeutic technique for the management of Barrett esophagus (BE)-related neoplasia. With the emergence of new endoluminal therapy including ...
    • Identifying Intestinal Metaplasia at the Squamocolumnar Junction by Using Optical Coherence Tomography 

      Evans, John A.; Bouma, Brett; Bressner, Jason; Shishkov, Milen Stefanov; Lauwers, Gregory Y.; Mino-Kenudson, Mari; Nishioka, Norman Shizuaki; Tearney, Guillermo James (Elsevier BV, 2007)
      Background: Optical coherence tomography (OCT) is an optical imaging method that produces high-resolution cross-sectional images of the esophagus. The accuracy of OCT for differentiating tissue types at the squamocolumnar ...
    • Image-Guided Biopsy in the Esophagus through Comprehensive Optical Frequency Domain Imaging and Laser Marking: A Study in Living Swine 

      Suter, Melissa; Jillella, Priyanka A.; Vakoc, Benjamin; Halpern, Elkan F.; Mino-Kenudson, Mari; Lauwers, Gregory Y.; Bouma, Brett; Nishioka, Norman Shizuaki; Tearney, Guillermo James (Elsevier BV, 2010)
      Background: Random biopsy esophageal surveillance can be subject to sampling errors, resulting in diagnostic uncertainty. Optical frequency domain imaging (OFDI) is a high-speed, 3-dimensional endoscopic microscopy technique. ...
    • Photometric stereo endoscopy 

      Parot, Vicente; Lim, Daryl; González, Germán; Traverso, Giovanni; Nishioka, Norman S.; Vakoc, Benjamin J.; Durr, Nicholas J. (Society of Photo-Optical Instrumentation Engineers, 2013)
      Abstract. While color video endoscopy has enabled wide-field examination of the gastrointestinal tract, it often misses or incorrectly classifies lesions. Many of these missed lesions exhibit characteristic three-dimensional ...
    • Reflectance Confocal Microscopy for the Diagnosis of Eosinophilic Esophagitis: a Pilot Study Conducted on Biopsy Specimens 

      Yoo, Hongki; Kang, DongKyun; Katz, Aubrey J.; Lauwers, Gregory Y.; Nishioka, Norman Shizuaki; Yagi, Yukako; Tanpowpong, Pornthep; Namati, Jacqueline; Bouma, Brett; Tearney, Guillermo James (Elsevier BV, 2011)
      Background: Diagnosis of eosinophilic esophagitis (EoE) currently requires endoscopic biopsy and histopathologic analysis of the biopsy specimens to count intraepithelial eosinophils. Reflectance confocal microscopy (RCM) ...
    • Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure 

      Gora, Michalina J.; Sauk, Jenny S.; Carruth, Robert W.; Gallagher, Kevin A.; Suter, Melissa J.; Nishioka, Norman S.; Kava, Lauren E.; Rosenberg, Mireille; Bouma, Brett E.; Tearney, Guillermo J. (2012)
      Here, we introduce “tethered capsule endomicroscopy,” that involves swallowing an optomechanically-engineered pill that captures cross-sectional, 30 μm (lateral) × 7 μm (axial) resolution, microscopic images of the gut ...