Browsing by Author "Kent, Michael"
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Evaluation of Rigid Bronchoscopy–Guided Percutaneous Dilational Tracheostomy. A Pilot Study
Majid, Adnan; Cheng, George Z.; Kent, Michael; Gangadharan, Sidhu; Whyte, Richard; Folch, Erik E (American Thoracic Society, 2014)Rationale: Rigid bronchoscopy–guided (RBG) percutaneous tracheostomy has been used in patients with morbid obesity, prior neck surgery, distorted airway anatomy, and uncorrected coagulopathy where standard percutaneous ... -
Experience with targeted next generation sequencing for the care of lung cancer: Insights into promises and limitations of genomic oncology in day-to-day practice
Rangachari, Deepa; Vanderlaan, Paul A; Le, Xiuning; Folch, Erik E; Kent, Michael; Gangadharan, Sidhu; Majid, Adnan; Haspel, Richard Lawrence; Joseph, Loren Jay; Huberman, Mark S.; Costa, Daniel Botelho (Elsevier BV, 2015)Introduction Tumor genotyping using single gene assays (SGAs) is standard practice in advanced non-small-cell lung cancer (NSCLC). We evaluated how the introduction of next generation sequencing (NGS) into day-to-day ... -
De novo pulmonary small cell carcinomas and large cell neuroendocrine carcinomas harboring EGFR mutations: Lack of response to EGFR inhibitors
Le, Xiuning; DeSai, Neelam V.; Majid, Adnan; Karp, Rebecca Sara; Huberman, Mark S.; Rangachari, Deepa; Kent, Michael; Gangadharan, Sidhu; Folch, Erik E; Vanderlaan, Paul A; Costa, Daniel Botelho (Elsevier BV, 2015)Introduction Epidermal growth factor receptor (EGFR) mutations are present in 10-20% of all non-small-cell lung cancers and predict for response to EGFR tyrosine kinase inhibitors (TKIs). However, the incidence of these ... -
Smoking status and self-reported race affect the frequency of clinically relevant oncogenic alterations in non-small-cell lung cancers at a United States-based academic medical practice
Yamaguchi, Norihiro; Vanderlaan, Paul A; Folch, Erik E; Boucher, David H.; Canepa, Hannah M.; Kent, Michael; Gangadharan, Sidhu; Majid, Adnan; Kocher, Olivier Nicolas; Goldstein, Michael A.; Huberman, Mark S.; Costa, Daniel Botelho (Elsevier BV, 2013)Introduction The identification of somatic genomic aberrations in non-small-cell lung cancer (NSCLC) is part of evidence-based practice guidelines for care of patients with NSCLC. We sought to establish the frequency and ... -
Success and failure rates of tumor genotyping techniques in routine pathological samples with non-small-cell lung cancer
Vanderlaan, Paul A; Yamaguchi, Norihiro; Folch, Erik E; Boucher, David H.; Kent, Michael; Gangadharan, Sidhu; Majid, Adnan; Goldstein, Michael A.; Huberman, Mark S.; Kocher, Olivier Nicolas; Costa, Daniel Botelho (Elsevier BV, 2014)Introduction—Identification of some somatic molecular alterations in non-small-cell lung cancer (NSCLC) has become evidence-based practice. The success and failure rate of using commercially-available tumor genotyping ...