Now showing items 1-4 of 4

    • Electron Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue 

      Ladinsky, Mark S.; Kieffer, Collin; Olson, Gregory; Deruaz, Maud; Vrbanac, Vladimir; Tager, Andrew M.; Kwon, Douglas S.; Bjorkman, Pamela J. (Public Library of Science, 2014)
      Critical aspects of HIV-1 infection occur in mucosal tissues, particularly in the gut, which contains large numbers of HIV-1 target cells that are depleted early in infection. We used electron tomography (ET) to image HIV-1 ...
    • HIV-infected T cells are migratory vehicles for viral dissemination 

      Murooka, Thomas; Deruaz, Maud; Marangoni, Francesco; Vrbanac, Vladimir D.; Seung, Edward N.; Von Andrian, Ulrich H.; Tager, Andrew Martin; Luster, Andrew David; Mempel, Thorsten Roman (2012)
      After host entry through mucosal surfaces, HIV-1 disseminates to lymphoid tissues to establish a generalized infection of the immune system. The mechanisms by which this virus spreads among permissive target cells locally ...
    • The Humanized BLT Mouse to Study HIV Transmission 

      Deruaz, Maud; Murooka, Thomas; Dudek, Timothy E; Vrbanac, VD; Tivet, T; Bankert, KC; Allen, Todd; Tager, Andrew Martin; Luster, Andrew David (BioMed Central, 2012)
    • IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection 

      Adoro, Stanley; Cubillos-Ruiz, Juan R.; Chen, Xi; Deruaz, Maud; Vrbanac, Vladimir D.; Song, Minkyung; Park, Suna; Murooka, Thomas T.; Dudek, Timothy E.; Luster, Andrew D.; Tager, Andrew M.; Streeck, Hendrik; Bowman, Brittany; Walker, Bruce D.; Kwon, Douglas S.; Lazarevic, Vanja; Glimcher, Laurie H. (Nature Pub. Group, 2015)
      Initial events after exposure determine HIV-1 disease progression, underscoring a critical need to understand host mechanisms that interfere with initial viral replication. Although associated with chronic HIV-1 control, ...