Browsing by Author "Deruaz, Maud"
Now showing items 1-5 of 5
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Electron Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue
Ladinsky, Mark S.; Kieffer, Collin; Olson, Gregory; Deruaz, Maud; Vrbanac, Vladimir; Tager, Andrew M.; Kwon, Douglas S.; Bjorkman, Pamela J. (Public Library of Science, 2014)Critical aspects of HIV-1 infection occur in mucosal tissues, particularly in the gut, which contains large numbers of HIV-1 target cells that are depleted early in infection. We used electron tomography (ET) to image HIV-1 ... -
HIV-infected T cells are migratory vehicles for viral dissemination
Murooka, Thomas; Deruaz, Maud; Marangoni, Francesco; Vrbanac, Vladimir; Seung, Edward N.; Von Andrian, Ulrich H.; Tager, Andrew Martin; Luster, Andrew David; Mempel, Thorsten Roman (2012)After host entry through mucosal surfaces, HIV-1 disseminates to lymphoid tissues to establish a generalized infection of the immune system. The mechanisms by which this virus spreads among permissive target cells locally ... -
The Humanized BLT Mouse to Study HIV Transmission
Deruaz, Maud; Murooka, Thomas; Dudek, Timothy E; Vrbanac, Vladimir; Tivet, T; Bankert, KC; Allen, Todd; Tager, Andrew Martin; Luster, Andrew David (BioMed Central, 2012) -
IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection
Adoro, Stanley; Cubillos-Ruiz, Juan R.; Chen, Xi; Deruaz, Maud; Vrbanac, Vladimir; Song, Minkyung; Park, Suna; Murooka, Thomas T.; Dudek, Timothy E.; Luster, Andrew D.; Tager, Andrew M.; Streeck, Hendrik; Bowman, Brittany; Walker, Bruce D.; Kwon, Douglas S.; Lazarevic, Vanja; Glimcher, Laurie H. (Nature Pub. Group, 2015)Initial events after exposure determine HIV-1 disease progression, underscoring a critical need to understand host mechanisms that interfere with initial viral replication. Although associated with chronic HIV-1 control, ... -
Intra- and extra-cellular environments contribute to the fate of HIV-1 infection
Ratnapriya, Sneha; Harris, Miranda; Chov, Angela; Vrbanac, Vladimir; Deruaz, Maud; Sodroski, Joseph; Herschhorn, Alon (Elsevier BV, 2021-08-31)HIV-1 entry into host cells leads to one of the following three alternative fates: (1) HIV-1 elimination by restriction factors, (2) establishment of HIV-1 latency, or (3) active viral replication in target cells. Here, ...