Now showing items 1-3 of 3

    • Dynamic Transcriptional Reprogramming Leads to Immunotherapeutic Vulnerabilities in Myeloma 

      Frede, Julia; Anand, Praveen; Sotudeh, Noori; Pinto, Ricardo A.; Nair, Monica S.; Stuart, Hannah; Yee, Andrew J.; Vijaykumar, Tushara; Waldschmidt, Johannes M.; Potdar, Sayalee; Kloeber, Jake A.; Kokkalis, Antonis; Dimitrova, Valeriya; Mann, Mason; Laubach, Jacob; Richardson, Paul; Anderson, Kenneth; Raje, Noopur; Knoechel, Birgit; Lohr, Jens (Springer Science and Business Media LLC, 2021-10-21)
    • Genomic discovery and clonal tracking in multiple myeloma by cell free DNA sequencing 

      Guo, Guangwu; Raje, Noopur; Seifer, Charles; Kloeber, Jake; Meyerson, Matthew Langer; Munshi, Nikhil C; Knoechel, Birgit; Lohr, Jens Guenter (Nature Publishing Group, 2018)
    • An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma 

      Drier, Yotam; Cotton, Matthew J.; Williamson, Kaylyn E.; Gillespie, Shawn M.; Ryan, Russell J.H.; Kluk, Michael J.; Carey, Christopher D.; Rodig, Scott J.; Sholl, Lynette M; Afrogheh, Amir H.; Faquin, William C.; Queimado, Lurdes; Qi, Jun; Wick, Michael J.; El-Naggar, Adel K.; Bradner, James E.; Moskaluk, Christopher A.; Aster, Jon C.; Knoechel, Birgit; Bernstein, Bradley E. (2016)
      Translocation events are frequent in cancer and may create chimeric fusions or ‘regulatory rearrangements’ that drive oncogene overexpression. Here we identify super-enhancer translocations that drive overexpression of the ...