Browsing by Author "Purdon, Patrick"

Now showing items 1-6 of 6

    • Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants 

      Cornelissen, Laura Louise; Kim, Seong-Eun; Purdon, Patrick Lee; Brown, Emery Neal; Berde, Charles Benjamin (eLife Sciences Organisation, Ltd., 2015)
      Electroencephalogram (EEG) approaches may provide important information about developmental changes in brain-state dynamics during general anesthesia. We used multi-electrode EEG, analyzed with multitaper spectral methods ...

    • Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness 

      Akeju, Oluwaseun; Loggia, Marco L; Catana, Ciprian; Pavone, Kara J; Vazquez, Rafael; Rhee, James; Contreras Ramirez, Violeta; Chonde, Daniel B; Izquierdo-Garcia, David; Arabasz, Grae; Hsu, Shirley; Habeeb, Kathleen; Hooker, Jacob M; Napadow, Vitaly; Brown, Emery N; Purdon, Patrick L (eLife Sciences Publications, Ltd, 2014)
      Understanding the neural basis of consciousness is fundamental to neuroscience research. Disruptions in cortico-cortical connectivity have been suggested as a primary mechanism of unconsciousness. By using a novel combination ...

    • Local cortical dynamics of burst suppression in the anaesthetized brain 

      Lewis, Laura D.; Ching, ShiNung; Weiner, Veronica S.; Peterfreund, Robert A.; Eskandar, Emad N.; Cash, Sydney S.; Brown, Emery N.; Purdon, Patrick L. (Oxford University Press, 2013)
      Burst suppression is an electroencephalogram pattern that consists of a quasi-periodic alternation between isoelectric ‘suppressions’ lasting seconds or minutes, and high-voltage ‘bursts’. It is characteristic of a profoundly ...

    • Spatiotemporal Dynamics of Dexmedetomidine-Induced Electroencephalogram Oscillations 

      Akeju, Oluwaseun; Kim, Seong-Eun; Vazquez, Rafael; Rhee, James; Pavone, Kara J.; Hobbs, Lauren E.; Purdon, Patrick L.; Brown, Emery N. (Public Library of Science, 2016)
      An improved understanding of the neural correlates of altered arousal states is fundamental for precise brain state targeting in clinical settings. More specifically, electroencephalogram recordings are now increasingly ...

    • Time-variant fMRI activity in the brainstem and higher structures in response to acupuncture 

      Napadow, Vitaly J.; Dhond, Rupali; Park, Kyungmo; Kim, Jieun; Makris, Nikos; Kwong, Kenneth Kin Man; Harris, Richard E.; Purdon, Patrick Lee; Kettner, Norman; Hui, Kathleen K.S. (Elsevier BV, 2009)
      Acupuncture modulation of activity in the human brainstem is not well known. This structure is plagued by physiological artifact in neuroimaging experiments. In addition, most studies have used short (<15min) block designs, ...

    • A Unified Point Process Probabilistic Framework to Assess Heartbeat Dynamics and Autonomic Cardiovascular Control 

      Chen, Zhe; Purdon, Patrick Lee; Brown, Emery Neal; Barbieri, Riccardo (Frontiers Research Foundation, 2012)
      In recent years, time-varying inhomogeneous point process models have been introduced for assessment of instantaneous heartbeat dynamics as well as specific cardiovascular control mechanisms and hemodynamics. Assessment ...