Now showing items 1-2 of 2

• #### CTL Responses of High Functional Avidity and Broad Variant Cross-Reactivity Are Associated with HIV Control ﻿

(Public Library of Science, 2012)
Cytotoxic T lymphocyte (CTL) responses targeting specific HIV proteins, in particular Gag, have been associated with relative control of viral replication $in$ $vivo$. However, Gag-specific CTL can also be detected in ...
• #### Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase ﻿

(2014)
The PTH receptor is one of the first GPCR found to sustain cAMP signaling after internalization of the ligand–receptor complex in endosomes. This unexpected model is adding a new dimension on how we think about GPCR ...