Now showing items 1-2 of 2

    • CTL Responses of High Functional Avidity and Broad Variant Cross-Reactivity Are Associated with HIV Control 

      Mothe, Beatriz; Llano, Anuska; Ibarrondo, Javier; Zamarreño, Jennifer; Schiaulini, Mattia; Miranda, Cristina; Ruiz-Riol, Marta; Berger, Christoph T.; Herrero, M. José; Palou, Eduard; Plana, Montse; Rolland, Morgane; Heckerman, David; Weiner, David; Paredes, Roger; Clotet, Bonaventura; Felber, Barbara K.; Pavlakis, George N.; Mullins, James I.; Brander, Christian; Khatri, Ashok; Pereyra, Florencia M.; Walker, Bruce David (Public Library of Science, 2012)
      Cytotoxic T lymphocyte (CTL) responses targeting specific HIV proteins, in particular Gag, have been associated with relative control of viral replication \(in\) \(vivo\). However, Gag-specific CTL can also be detected in ...
    • Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase 

      Gidon, Alexandre; Al-Bataineh, Mohammad M.; Jean-Alphonse, Frederic G.; Stevenson, Hilary; Watanabe, Tomoyuki; Louet, Claire; Khatri, Ashok; Calero, Guillermo; Pastor-Soler, Núria M.; Gardella, Thomas J.; Vilardaga, Jean-Pierre (2014)
      The PTH receptor is one of the first GPCR found to sustain cAMP signaling after internalization of the ligand–receptor complex in endosomes. This unexpected model is adding a new dimension on how we think about GPCR ...