Browsing by Author "Osborn, Teresia"

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Molecular Basis of Filamin A-FilGAP Interaction and Its Impairment in Congenital Disorders Associated with Filamin A Mutations

Heikkinen, Outi; Pentikäinen, Olli T.; Kasza, Karen E.; Kupiainen, Olga; Permi, Perttu; Kilpeläinen, Ilkka; Ylänne, Jari; Nakamura, Fumihiko; Osborn, Teresia M.; Weitz, David A.; Hartwig, John Henry; Stossel, Thomas Peter (Public Library of Science, 2009)

Background: Mutations in filamin A (FLNa), an essential cytoskeletal protein with multiple binding partners, cause developmental anomalies in humans. Methodology/principal findings: We determined the structure of the 23rd ...
A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)

Smith, Gaynor A.; Rocha, Emily M.; Rooney, Thomas; Barneoud, Pascal; McLean, Jesse R.; Beagan, Jonathan; Osborn, Teresia; Coimbra, Madeleine; Luo, Yongyi; Hallett, Penelope J.; Isacson, Ole (Public Library of Science, 2015)

Dopaminergic neurons in the substantia nigra pars compacta (SNpc) are characterized by the expression of genes required for dopamine synthesis, handling and reuptake and the expression of these genes is largely controlled ...