Now showing items 1-10 of 10

    • The Association Between Talc Use and Ovarian Cancer 

      Cramer, Daniel William; Vitonis, Allison F.; Terry, Kathryn Lynne; Welch, William Robert; Titus, Linda J. (Ovid Technologies (Wolters Kluwer Health), 2016)
      BACKGROUND: Multiple studies of ovarian cancer and genital talc use have led only to consensus about possible carcinogenicity. Seeking greater clarity, we examined this association in 2,041 cases with epithelial ovarian ...
    • The Association Between Talc Use and Ovarian Cancer: A Retrospective Case–Control Study in Two US States 

      Cramer, Daniel W.; Vitonis, Allison F.; Terry, Kathryn L.; Welch, William R.; Titus, Linda J. (Lippincott Williams & Wilkins, 2015)
      Background: Multiple studies of ovarian cancer and genital talc use have led only to consensus about possible carcinogenicity. Seeking greater clarity, we examined this association in 2,041 cases with epithelial ovarian ...
    • Autoantibody profiling to identify biomarkers of key pathogenic pathways in mucinous ovarian cancer 

      Tang, Liangdan; Yang, Junzheng; Ng, Shu-Kay; Rodriguez, Noah; Choi, Pui-Wah; Vitonis, Allison; Wang, Kui; McLachlan, Geoffrey J.; Caiazzo, Robert J.; Liu, Brian C.-S.; Welch, William Robert; Cramer, Daniel William; Berkowitz, Ross Stuart; Ng, Shu-Wing (Elsevier BV, 2010)
      Mucinous epithelial ovarian cancers are clinically and morphologically distinct from the other histopathologic subtypes of ovarian cancer. Unlike other ovarian subtypes, epidemiologic studies have indicated that tobacco ...
    • Correlates of the preoperative level of CA125 at presentation of ovarian cancer 

      Cramer, Daniel William; Vitonis, Allison F.; Welch, William Robert; Terry, Kathryn Lynne; Goodman, Annekathryn; Rueda, Bo Ruben; Berkowitz, Ross Stuart (Elsevier BV, 2010)
      Objective CA125 at presentation of ovarian cancer carries important prognostic significance; but, other than tumor characteristics, little is known about factors that influence CA125 levels. We examined the effect of ...
    • Differential hRad17 Expression by Histologic Subtype of Ovarian Cancer 

      Young, Jennifer L; Koon, E Colin; Kwong, Joseph; Welch, William Robert; Muto, Michael George; Berkowitz, Ross Stuart; Mok, Samuel C (BioMed Central, 2011)
      Background: In the search for unique ovarian cancer biomarkers, ovarian specific cDNA microarray analysis identified hRad17, a cell cycle checkpoint protein, as over-expressed in ovarian cancer. The aim of this study was ...
    • Endometriosis-Associated Ovarian Cancer: A Review of Pathogenesis 

      Worley, Michael Joe; Welch, William Robert; Berkowitz, Ross Stuart; Ng, Shu-Wing (Molecular Diversity Preservation International (MDPI), 2013)
      Endometriosis is classically defined as the presence of endometrial glands and stroma outside of the endometrial lining and uterine musculature. With an estimated frequency of 5%–10% among women of reproductive age, ...
    • Etiology and Pathogenesis of Epithelial Ovarian Cancer 

      Mok, Samuel C.; Kwong, Joseph; Welch, William R.; Samimi, Goli; Ozbun, Laurent; Bonome, Tomas; Birrer, Michael J.; Berkowitz, Ross S.; Wong, Kwong-Kwok (IOS Press, 2007)
      Ovarian cancer is complex disease composed of different histological grades and types. However, the underlying molecular mechanisms involved in the development of different phenotypes remain largely unknown. Epidemiological ...
    • Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells 

      Zhang, Yanli; Kwok, Jamie Sui-Lam; Choi, Pui-Wah; Liu, Minghua; Yang, Junzheng; Singh, Margit; Ng, Shu-Kay; Welch, William R.; Muto, Michael G.; Tsui, Stephen KW; Sugrue, Stephen P.; Berkowitz, Ross S.; Ng, Shu-Wing (Impact Journals LLC, 2016)
      Unlike many other human solid tumors, ovarian tumors express many epithelial markers at a high level for cell growth and local invasion. The phosphoprotein Pinin plays a key role in epithelial cell identity. We showed that ...
    • Prognostic significance and predictors of the neutrophil-to-lymphocyte ratio in ovarian cancer 

      Williams, Kristina; Labidi-Galy, S. Intidhar; Terry, Kathryn Lynne; Vitonis, Allison F.; Welch, William Robert; Goodman, Annekathryn; Cramer, Daniel William (Elsevier BV, 2014)
      Objective: To investigate the neutrophil-to-lymphocyte ratio (NLR) from peripheral blood, a general measure of inflammation, in ovarian cancer. Methods: White cell counts and CA125 levels before treatment, tumor features, ...
    • Puerperal mastitis: a reproductive event of importance affecting anti-mucin antibody levels and ovarian cancer risk 

      Cramer, Daniel William; Williams, Kristina; Vitonis, Allison F.; Yamamoto, Hidemi S.; Stuebe, Alison; Welch, William Robert; Titus, Linda; Fichorova, Raina Nakova (Springer Nature, 2013)
      Purpose: Test the hypothesis that puerperal mastitis may alter immunity related to the mucin (MUC) family of glycoproteins and lower risk of ovarian cancer. Methods: In two case–control studies conducted in New England ...