Now showing items 1-4 of 4

    • Cell type specificity of neurovascular coupling in cerebral cortex 

      Uhlirova, Hana; Kılıç, Kıvılcım; Tian, Peifang; Thunemann, Martin; Desjardins, Michèle; Saisan, Payam A; Sakadžić, Sava; Ness, Torbjørn V; Mateo, Celine; Cheng, Qun; Weldy, Kimberly L; Razoux, Florence; Vandenberghe, Matthieu; Cremonesi, Jonathan A; Ferri, Christopher GL; Nizar, Krystal; Sridhar, Vishnu B; Steed, Tyler C; Abashin, Maxim; Fainman, Yeshaiahu; Masliah, Eliezer; Djurovic, Srdjan; Andreassen, Ole A; Silva, Gabriel A; Boas, David A; Kleinfeld, David; Buxton, Richard B; Einevoll, Gaute T; Dale, Anders M; Devor, Anna (eLife Sciences Publications, Ltd, 2016)
      Identification of the cellular players and molecular messengers that communicate neuronal activity to the vasculature driving cerebral hemodynamics is important for (1) the basic understanding of cerebrovascular regulation ...
    • Large arteriolar component of oxygen delivery implies safe margin of oxygen supply to cerebral tissue 

      Sakadžić, Sava; Mandeville, Emiri T.; Gagnon, Louis; Musacchia, Joseph J.; Yaseen, Mohammad A.; Yucel, Meryem A; Lefebvre, Joel; Lesage, Frédéric; Dale, Anders M.; Eikermann-Haerter, Katharina; Ayata, Cenk; Srinivasan, Vivek J.; Lo, Eng H.; Devor, Anna; Boas, David A. (2014)
      What is the organization of cerebral microvascular oxygenation and morphology that allows adequate tissue oxygenation at different activity levels? We address this question in the mouse cerebral cortex using microscopic ...
    • Modeling of Cerebral Oxygen Transport Based on In vivo Microscopic Imaging of Microvascular Network Structure, Blood Flow, and Oxygenation 

      Gagnon, Louis; Smith, Amy F.; Boas, David A.; Devor, Anna; Secomb, Timothy W.; Sakadžić, Sava (Frontiers Media S.A., 2016)
      Oxygen is delivered to brain tissue by a dense network of microvessels, which actively control cerebral blood flow (CBF) through vasodilation and contraction in response to changing levels of neural activity. Understanding ...
    • Neurovascular Network Explorer 1.0: a database of 2-photon single-vessel diameter measurements with MATLAB® graphical user interface 

      Sridhar, Vishnu B.; Tian, Peifang; Dale, Anders M.; Devor, Anna; Saisan, Payam A. (Frontiers Media S.A., 2014)
      We present a database client software—Neurovascular Network Explorer 1.0 (NNE 1.0)—that uses MATLAB® based Graphical User Interface (GUI) for interaction with a database of 2-photon single-vessel diameter measurements from ...