Now showing items 1-12 of 12

    • Aspirin Use and Risk of Atrial Fibrillation in the Physicians' Health Study 

      Ofman, Peter; Petrone, Andrew B.; Peralta, Adelqui; Hoffmeister, Peter; Albert, Christine M.; Djousse, Luc; Gaziano, J. Michael; Rahilly‐Tierney, Catherine R. (Blackwell Publishing Ltd, 2014)
      Background: Inflammatory processes have been associated with an increased risk of atrial fibrillation (AF), potentially allowing for preventive therapy by anti‐inflammatory agents such as aspirin. However, the effect of ...
    • Association between adiponectin and heart failure risk in the Physicians' Health Study 

      Djoussé, Luc; Wilk, Jemma B.; Hanson, Naomi Q.; Glynn, Robert; Tsai, Michael Y.; Gaziano, J. Michael (2012)
      Limited data are available on the association between adiponectin and incident heart failure. In the current ancillary study to the Physicians' Health Study, we used a prospective nested-case control design to examine ...
    • Consumption of Fried Foods and Risk of Heart Failure in the Physicians' Health Study 

      Djoussé, Luc; Petrone, Andrew B.; Gaziano, J. Michael (Blackwell Publishing Ltd, 2015)
      Background: Consumption of fried foods is highly prevalent in the Western dietary pattern. Though limited studies have reported a positive association between frequency of fried food intake and risk of coronary artery ...
    • Dietary Magnesium and Genetic Interactions in Diabetes and Related Risk Factors: A Brief Overview of Current Knowledge 

      Hruby, Adela; McKeown, Nicola M.; Song, Yiqing; Djoussé, Luc (MDPI, 2013)
      Nutritional genomics has exploded in the last decade, yielding insights—both nutrigenomic and nutrigenetic—into the physiology of dietary interactions and our genes. Among these are insights into the regulation of magnesium ...
    • Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure 

      Smith, J. Gustav; Felix, Janine F.; Morrison, Alanna C.; Kalogeropoulos, Andreas; Trompet, Stella; Wilk, Jemma B.; Gidlöf, Olof; Wang, Xinchen; Morley, Michael; Mendelson, Michael; Joehanes, Roby; Ligthart, Symen; Shan, Xiaoyin; Bis, Joshua C.; Wang, Ying A.; Sjögren, Marketa; Ngwa, Julius; Brandimarto, Jeffrey; Stott, David J.; Aguilar, David; Rice, Kenneth M.; Sesso, Howard D.; Demissie, Serkalem; Buckley, Brendan M.; Taylor, Kent D.; Ford, Ian; Yao, Chen; Liu, Chunyu; Sotoodehnia, Nona; van der Harst, Pim; Stricker, Bruno H. Ch.; Kritchevsky, Stephen B.; Liu, Yongmei; Gaziano, J. Michael; Hofman, Albert; Moravec, Christine S.; Uitterlinden, André G.; Kellis, Manolis; van Meurs, Joyce B.; Margulies, Kenneth B.; Dehghan, Abbas; Levy, Daniel; Olde, Björn; Psaty, Bruce M.; Cupples, L. Adrienne; Jukema, J. Wouter; Djousse, Luc; Franco, Oscar H.; Boerwinkle, Eric; Boyer, Laurie A.; Newton-Cheh, Christopher; Butler, Javed; Vasan, Ramachandran S.; Cappola, Thomas P.; Smith, Nicholas L. (Public Library of Science, 2016)
      Failure of the human heart to maintain sufficient output of blood for the demands of the body, heart failure, is a common condition with high mortality even with modern therapeutic alternatives. To identify molecular ...
    • Fried Food Consumption and Cardiovascular Health: A Review of Current Evidence 

      Gadiraju, Taraka V.; Patel, Yash; Gaziano, J. Michael; Djoussé, Luc (MDPI, 2015)
      Fried food consumption and its effects on cardiovascular disease are still subjects of debate. The objective of this review was to summarize current evidence on the association between fried food consumption and cardiovascular ...
    • Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry 

      Nettleton, Jennifer A.; Follis, Jack L.; Ngwa, Julius S.; Smith, Caren E.; Ahmad, Shafqat; Tanaka, Toshiko; Wojczynski, Mary K.; Voortman, Trudy; Lemaitre, Rozenn N.; Kristiansson, Kati; Nuotio, Marja-Liisa; Houston, Denise K.; Perälä, Mia-Maria; Qi, Qibin; Sonestedt, Emily; Manichaikul, Ani; Kanoni, Stavroula; Ganna, Andrea; Mikkilä, Vera; North, Kari E.; Siscovick, David S.; Harald, Kennet; Mckeown, Nicola M.; Johansson, Ingegerd; Rissanen, Harri; Liu, Yongmei; Lahti, Jari; Hu, Frank B.; Bandinelli, Stefania; Rukh, Gull; Rich, Stephen; Booij, Lisanne; Dmitriou, Maria; Ax, Erika; Raitakari, Olli; Mukamal, Kenneth; Männistö, Satu; Hallmans, Göran; Jula, Antti; Ericson, Ulrika; Jacobs,, David R.; Van Rooij, Frank J. A.; Deloukas, Panos; Sjögren, Per; Kähönen, Mika; Djousse, Luc; Perola, Markus; Barroso, Inês; Hofman, Albert; Stirrups, Kathleen; Viikari, Jorma; Uitterlinden, André G.; Kalafati, Ioanna P.; Franco, Oscar H.; Mozaffarian, Dariush; Salomaa, Veikko; Borecki, Ingrid B.; Knekt, Paul; Kritchevsky, Stephen B.; Eriksson, Johan G.; Dedoussis, George V.; Qi, Lu; Ferrucci, Luigi; Orho-Melander, Marju; Zillikens, M. Carola; Ingelsson, Erik; Lehtimäki, Terho; Renström, Frida; Cupples, L. Adrienne; Loos, Ruth J. F.; Franks, Paul W. (Oxford University Press, 2015)
      Obesity is highly heritable. Genetic variants showing robust associations with obesity traits have been identified through genome-wide association studies. We investigated whether a composite score representing healthy ...
    • Genetically Elevated Fetuin-A Levels, Fasting Glucose Levels, and Risk of Type 2 Diabetes: The Cardiovascular Health Study* 

      Jensen, Majken K.; Bartz, Traci M.; Djoussé, Luc; Kizer, Jorge R.; Zieman, Susan J.; Rimm, Eric B.; Siscovick, David S.; Psaty, Bruce M.; Ix, Joachim H.; Mukamal, Kenneth J. (American Diabetes Association, 2013)
      OBJECTIVE Fetuin-A levels are associated with higher risk of type 2 diabetes, but it is unknown if the association is causal. We investigated common (>5%) genetic variants in the fetuin-A gene (AHSG) fetuin-A levels, fasting ...
    • Nut Consumption and Risk of Atrial Fibrillation in the Physicians' Health Study 

      Khawaja, O.; Gaziano, John Michael; Djousse, Luc (BioMed Central, 2012)
      Background: Atrial Fibrillation is highly prevalent in clinical practice affecting approximately 2.3 million people in USA and 4.5 million people in European Union. The aim of the study was to examine the association between ...
    • Plasma Fatty Acid Binding Protein 4 and Risk of Sudden Cardiac Death in Older Adults 

      Djoussé, Luc; Maziarz, Marlena; Biggs, Mary L.; Ix, Joachim H.; Zieman, Susan J.; Kizer, Jorge R.; Lemaitre, Rozenn N.; Mozaffarian, Dariush; Tracy, Russell P.; Mukamal, Kenneth J.; Siscovick, David S.; Sotoodehnia, Nona (Hindawi Publishing Corporation, 2013)
      Although fatty acid binding protein 4 (FABP4) may increase risk of diabetes and exert negative cardiac inotropy, it is unknown whether plasma concentrations of FABP4 are associated with incidence of sudden cardiac death ...
    • Plasma Phospholipid Saturated Fatty Acids and Incident Atrial Fibrillation: The Cardiovascular Health Study 

      Fretts, Amanda M.; Mozaffarian, Dariush; Siscovick, David S.; Djousse, Luc; Heckbert, Susan R.; King, Irena B.; McKnight, Barbara; Sitlani, Colleen; Sacks, Frank M.; Song, Xiaoling; Sotoodehnia, Nona; Spiegelman, Donna; Wallace, Erin R.; Lemaitre, Rozenn N. (Blackwell Publishing Ltd, 2014)
      Background: Prior studies suggest that circulating fatty acids may influence the risk of atrial fibrillation (AF), but little is known about the associations of circulating saturated fatty acids with risk of AF. Methods ...
    • Total and High-Molecular-Weight Adiponectin and Risk of Incident Diabetes in Older People 

      Kizer, Jorge R.; Arnold, Alice M.; Benkeser, David; Ix, Joachim H.; Djousse, Luc; Zieman, Susan J.; Barzilay, Joshua I.; Tracy, Russell P.; Mantzoros, Christos S.; Siscovick, David S.; Mukamal, Kenneth J. (American Diabetes Association, 2012)
      OBJECTIVE To delineate the associations of total adiponectin, high-molecular-weight (HMW) adiponectin, and the HMW-to-total adiponectin ratio with diabetes in older adults. RESEARCH DESIGN AND METHODS Total and HMW adiponectin ...