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    • Phenotypic Spectrum Caused by Transgenic Overexpression of Activated Akt in the Heart 

      Matsui, Takashi; Li, Ling; Wu, Justina C.; Cook, Stuart; Nagoshi, Tomohisa; Picard, Michael Howard; Liao, Ronglih; Rosenzweig, Anthony (American Society for Biochemistry & Molecular Biology (ASBMB), 2002)
      The serine-threonine kinase, Akt, inhibits cardiomyocyte apoptosis acutely both in vitro and in vivo. However, the effects of chronic Akt activation in the heart are unknown. To address this issue, we generated transgenic ...