Browsing by Author "Ciaranello, Andrea"
Now showing items 1-9 of 9
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Cost-effectiveness of first-line antiretroviral therapy for HIV-infected African children less than 3 years of age
Ciaranello, Andrea L.; Doherty, Kathleen; Penazzato, Martina; Lindsey, Jane C.; Harrison, Linda; Kelly, Kathleen; Walensky, Rochelle P.; Essajee, Shaffiq; Losina, Elena; Muhe, Lulu; Wools-Kaloustian, Kara; Ayaya, Samuel; Weinstein, Milton C.; Palumbo, Paul; Freedberg, Kenneth A. (Lippincott Williams & Wilkins, 2015)Background: The International Maternal, Pediatric, and Adolescent Clinical Trials P1060 trial demonstrated superior outcomes for HIV-infected children less than 3 years old initiating antiretroviral therapy (ART) with ... -
Cost-Effectiveness of World Health Organization 2010 Guidelines for Prevention of Mother-to-Child HIV Transmission in Zimbabwe
Perez, Freddy; Engelsmann, Barbara; Mushavi, Angela; Rusibamayila, Asinath; Keatinge, Jo; Park, Ji-Eun; Maruva, Matthews; Wood, Robin; Dabis, Francois; Ciaranello, Andrea Lynne; Walensky, Rochelle P.; Cerda, Rodrigo; Freedberg, Kenneth Alan (Oxford University Press, 2012)Background. In 2010, the World Health Organization (WHO) released revised guidelines for prevention of mother-to-child human immunodeficiency virus (HIV) transmission (PMTCT). We projected clinical impacts, costs, and ... -
Estimating age-based antiretroviral therapy costs for HIV-infected children in resource-limited settings based on World Health Organization weight-based dosing recommendations
Doherty, Kathleen; Essajee, Shaffiq; Penazzato, Martina; Holmes, Charles; Resch, Stephen; Ciaranello, Andrea (BioMed Central, 2014)Background: Pediatric antiretroviral therapy (ART) has been shown to substantially reduce morbidity and mortality in HIV-infected infants and children. To accurately project program costs, analysts need accurate estimations ... -
Evolution of resistance in paediatric patients with failure on antiretroviral therapy
Orrell, C; Levison, J; Ciaranello, A; Bekker, L; Kuritzkes, D; Freedberg, Kenneth Alan; Wood, R (International AIDS Society, 2012) -
Point-of-Care CD4 Testing to Inform Selection of Antiretroviral Medications in South African Antenatal Clinics: A Cost-Effectiveness Analysis
Ciaranello, Andrea L.; Myer, Landon; Kelly, Kathleen; Christensen, Sarah; Daskilewicz, Kristen; Doherty, Katie; Bekker, Linda-Gail; Hou, Taige; Wood, Robin; Francke, Jordan A.; Wools-Kaloustian, Kara; Freedberg, Kenneth A.; Walensky, Rochelle P. (Public Library of Science, 2015)Background: Many prevention of mother-to-child HIV transmission (PMTCT) programs currently prioritize antiretroviral therapy (ART) for women with advanced HIV. Point-of-care (POC) CD4 assays may expedite the selection of ... -
Prenatal Transmission of Syphilis and Human Immunodeficiency Virus in Brazil: Achieving Regional Targets for Elimination
Cerda, Rodrigo; Perez, Freddy; Domingues, Rosa Maria S.M.; Luz, Paula M.; Grinsztejn, Beatriz; Veloso, Valdilea G.; Caffe, Sonja; Francke, Jordan A.; Freedberg, Kenneth A.; Ciaranello, Andrea L. (Oxford University Press, 2015)Background. The Pan-American Health Organization has called for reducing (1) human immunodeficiency virus (HIV) mother-to-child transmission (MTCT) to ≤0.30 infections/1000 live births (LB), (2) HIV MTCT risk to ≤2.0%, and ... -
Scaling Up the 2010 World Health Organization HIV Treatment Guidelines in Resource-Limited Settings: A Model-Based Analysis
Walensky, Rochelle P.; Wood, Robin; Ciaranello, Andrea Lynne; Paltiel, A. David; Lorenzana, Sarah B.; Anglaret, Xavier; Stoler, Adam W.; Freedberg, Kenneth Alan (Public Library of Science, 2010)Background: The new 2010 World Health Organization (WHO) HIV treatment guidelines recommend earlier antiretroviral therapy (ART) initiation (CD4,350 cells/ml instead of CD4,200 cells/ml), multiple sequential ART regimens, ... -
Validation and Calibration of a Computer Simulation Model of Pediatric HIV Infection
Ciaranello, Andrea L.; Morris, Bethany L.; Walensky, Rochelle P.; Weinstein, Milton C.; Ayaya, Samuel; Doherty, Kathleen; Leroy, Valeriane; Hou, Taige; Desmonde, Sophie; Lu, Zhigang; Noubary, Farzad; Patel, Kunjal; Ramirez-Avila, Lynn; Losina, Elena; Seage III, George R.; Freedberg, Kenneth A. (Public Library of Science, 2013)Background: Computer simulation models can project long-term patient outcomes and inform health policy. We internally validated and then calibrated a model of HIV disease in children before initiation of antiretroviral ... -
What Will it Take to Eliminate Pediatric HIV? Reaching WHO Target Rates of Mother-to-Child HIV Transmission in Zimbabwe: A Model-Based Analysis
Perez, Freddy; Keatinge, Jo; Park, Ji-Eun; Engelsmann, Barbara; Maruva, Matthews; Dabis, Francois; Chu, Jennifer; Rusibamayila, Asinath; Mushavi, Angela; Walensky, Rochelle P.; Ciaranello, Andrea Lynne; Freedberg, Kenneth Alan (Public Library of Science, 2012)Background: The World Health Organization (WHO) has called for the “virtual elimination” of pediatric HIV: a mother-to-child HIV transmission (MTCT) risk of less than 5%. We investigated uptake of prevention of MTCT (PMTCT) ...