Browsing by Author "Khalili, Hamed"
Now showing items 1-7 of 7
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Early life environment and natural history of inflammatory bowel diseases
Guo, Abra Y; Stevens, Betsy W; Wilson, Robin G; Russell, Caitlin N; Cohen, Melissa A; Sturgeon, Holly C; Thornton, Anna; Giallourakis, Cosmas; Khalili, Hamed; Nguyen, Deanna D; Sauk, Jenny; Yajnik, Vijay; Xavier, Ramnik J; Ananthakrishnan, Ashwin N (BioMed Central, 2014)Background: Early life exposures may modify risk of inflammatory bowel diseases (IBD; Crohn’s disease (CD), ulcerative colitis (UC)). However, the relationship between early life exposures and natural history of IBD has ... -
Endogenous Levels of Circulating Androgens and Risk of Crohn's Disease and Ulcerative Colitis Among Women: A Nested Case–Control Study from the Nurses' Health Study Cohorts
Khalili, Hamed; Ananthakrishnan, Ashwin N.; Konijeti, Gauree G.; Higuchi, Leslie M.; Fuchs, Charles S.; Richter, James M.; Tworoger, Shelley S.; Hankinson, Susan E.; Chan, Andrew T. (Lippincott Williams & Wilkins, 2015)Background: Androgens, which are known to be altered by exogenous hormone use, have recently been linked to alterations of the gut microbiome and mucosal immune function. No study has evaluated the association between ... -
Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability
Luther, Jay; Garber, John J.; Khalili, Hamed; Dave, Maneesh; Bale, Shyam Sundhar; Jindal, Rohit; Motola, Daniel L.; Luther, Sanjana; Bohr, Stefan; Jeoung, Soung Won; Deshpande, Vikram; Singh, Gurminder; Turner, Jerrold R.; Yarmush, Martin L.; Chung, Raymond T.; Patel, Suraj J. (2015)BACKGROUND & AIMS Emerging data suggest that changes in intestinal permeability and increased gut microbial translocation contribute to the inflammatory pathway involved in nonalcoholic steatohepatitis (NASH) development. ... -
Identification and Characterization of a Novel Association between Dietary Potassium and Risk of Crohn’s Disease and Ulcerative Colitis
Khalili, Hamed; Malik, Sakshi; Ananthakrishnan, Ashwin N.; Garber, John J.; Higuchi, Leslie M.; Joshi, Amit; Peloquin, Joanna; Richter, James M.; Stewart, Kathleen O.; Curhan, Gary C.; Awasthi, Amit; Yajnik, Vijay; Chan, Andrew T. (Frontiers Media S.A., 2016)Background: Recent animal studies have identified that dietary salt intake may modify the risk and progression of autoimmune disorders through modulation of the IL-23/TH17 pathway, which is critical in the pathogenesis of ... -
Physical activity and risk of inflammatory bowel disease: prospective study from the Nurses’ Health Study cohorts
Khalili, Hamed; Ananthakrishnan, Ashwin N; Konijeti, Gauree G; Liao, Xiaomei; Higuchi, Leslie M; Fuchs, Charles S; Spiegelman, Donna; Richter, James M; Korzenik, Joshua R; Chan, Andrew T (BMJ Publishing Group Ltd., 2013)Objective: To examine the association between physical activity and risk of ulcerative colitis and Crohn’s disease. Design: Prospective cohort study. Setting: Nurses’ Health Study and Nurses’ Health Study II. Participants: ... -
A Prospective Study of Periodontal Disease and Risk of Gastric and Duodenal Ulcer in Male Health Professionals
Boylan, Matthew R; Khalili, Hamed; Huang, Edward S; Michaud, Dominique S; Izard, Jacques; Joshipura, Kaumudi J; Chan, Andrew T (Nature Publishing Group, 2014)OBJECTIVES: Periodontal disease has been associated with higher circulating levels of inflammatory markers and conditions associated with chronic inflammation, including vascular disease, diabetes mellitus, and cancer. ... -
Use of Proton Pump Inhibitors and Risk of Hip Fracture in Relation to Dietary and Lifestyle Factors: A Prospective Cohort Study
Khalili, Hamed; Huang, Edward S.; Jacobson, Brian C.; Camargo, Carlos Arturo; Feskanich, Diane; Chan, Andrew Tan (BMJ Publishing Group, 2012)Objective: To examine the association between chronic use of proton pump inhibitors (PPIs) and risk of hip fracture. Design Prospective cohort study. Setting: Nurses’ Health Study, which originally recruited from the 11 ...