Browsing by Author "Priebe, Gregory"

Now showing items 1-4 of 4

    • Efficacy of Antibody to PNAG Against Keratitis Caused by Fungal Pathogens 

      Zhao, Ge; Zaidi, Tanweer S.; Bozkurt-Guzel, Cagla; Zaidi, Tauqeer H.; Lederer, James A.; Priebe, Gregory P.; Pier, Gerald B. (The Association for Research in Vision and Ophthalmology, 2016)
      Purpose Developing immunotherapies for fungal eye infections is a high priority. We analyzed fungal pathogens for expression of the surface polysaccharide, poly-N-acetyl glucosamine (PNAG), and used a mouse model of ocular ...

    • Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures 

      Lieberman, Tami D.; Flett, Kelly B.; Yelin, Idan; Martin, Thomas R.; McAdam, Alexander J.; Priebe, Gregory P.; Kishony, Roy (2014)
      Advances in sequencing have enabled the identification of mutations acquired by bacterial pathogens during infection1-10. However, it remains unclear whether adaptive mutations fix in the population or lead to pathogen ...

    • An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and Pathogenicity 

      Schaefers, Matthew M.; Liao, Tiffany L.; Boisvert, Nicole M.; Roux, Damien; Yoder-Himes, Deborah; Priebe, Gregory P. (Public Library of Science, 2017)
      Burkholderia dolosa is a member of the Burkholderia cepacia complex (BCC), which is a group of bacteria that cause chronic lung infection in patients with cystic fibrosis (CF) and can be associated with outbreaks carrying ...

    • Trehalose Biosynthesis Promotes Pseudomonas aeruginosa Pathogenicity in Plants 

      Djonović, Slavica; Urbach, Jonathan M.; Drenkard, Eliana Patricia; Bush, Jenifer; Feinbaum, Rhonda Lorin; Ausubel, Jonathan Lee; Traficante, David; Risech, Martina; Kocks, Christine; Fischbach, Michael A.; Priebe, Gregory Paul; Ausubel, Frederick M. (Public Library of Science, 2013)
      Pseudomonas aeruginosa strain PA14 is a multi-host pathogen that infects plants, nematodes, insects, and vertebrates. Many PA14 factors are required for virulence in more than one of these hosts. Noting that plants have a ...