Browsing by Author "Loeken, Mary"
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Embryonic Stem Cell Proliferation Stimulated By Altered Anabolic Metabolism From Glucose Transporter 2-Transported Glucosamine
Jung, Jin Hyuk; Iwabuchi, Kumiko; Yang, Zhihong; Loeken, Mary R. (Nature Publishing Group, 2016)The hexose transporter, GLUT2 (SLC2A2), which is expressed by mouse embryos, is important for survival before embryonic day 10.5, but its function in embryos is unknown. GLUT2 can transport the amino sugar glucosamine ... -
Pax3 Stimulates p53 Ubiquitination and Degradation Independent of Transcription
Wang, Xiaodan; Morgan, Sarah C.; Loeken, Mary Rose (Public Library of Science, 2011)Background: Pax3 is a developmental transcription factor that is required for neural tube and neural crest development. We previously showed that inactivating the p53 tumor suppressor protein prevents neural tube and cardiac ...