Now showing items 1-4 of 4

    • 14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila 

      Le, Thao Phuong; Vuong, Linh Thuong; Kim, Ah-Ram; Hsu, Ya-Chieh; Choi, Kwang-Wook (Nature Publishing Group, 2016)
      14-3-3 family proteins regulate multiple signalling pathways. Understanding biological functions of 14-3-3 proteins has been limited by the functional redundancy of conserved isotypes. Here we provide evidence that 14-3-3 ...
    • Discovery and In Vivo Characterization of Long Noncoding RNAs 

      Liapis, Stephen Constantine (2016-05-17)
      The noncoding genome, or the portion of the genome that does not encode for proteins, encompasses >95% of the human genome. It has been found that the majority of disease-associated genetic variants identified by genome-wide ...
    • Emerging interactions between skin stem cells and their niches 

      Hsu, Ya-Chieh; Li, Lishi; Fuchs, Elaine (Nature Publishing Group, 2014)
      The skin protects mammals from insults, infection and dehydration and enables thermoregulation and sensory perception. Various skin-resident cells carry out these diverse functions. Constant turnover of cells and healing ...
    • Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development 

      Perdigoto, Carolina N.; Dauber, Katherine L.; Bar, Carmit; Tsai, Pai-Chi; Valdes, Victor J.; Cohen, Idan; Santoriello, Francis J.; Zhao, Dejian; Zheng, Deyou; Hsu, Ya-Chieh; Ezhkova, Elena (Public Library of Science, 2016)
      An increasing amount of evidence indicates that developmental programs are tightly regulated by the complex interplay between signaling pathways, as well as transcriptional and epigenetic processes. Here, we have uncovered ...