Browsing by Author "Mekkaoui, Choukri"
Now showing items 1-8 of 8
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Diffusion MRI Tractography of the Developing Human Fetal Heart
Mekkaoui, Choukri; Porayette, Prashob; Jackowski, Marcel P.; Kostis, William J.; Dai, Guangping; Sanders, Stephen; Sosnovik, David E. (Public Library of Science, 2013)Objective: Human myocardium has a complex and anisotropic 3D fiber pattern. It remains unknown, however, when in fetal life this anisotropic pattern develops and whether the human heart is structurally fully mature at ... -
Diffusion MRI Tractography of the Human Heart \(In\) \(Vivo\) at End-Diastole and End-Systole
Mekkaoui, Choukri; Nielles-Vallespin, Sonia; Gatehouse, Peter D; Jackowski, Marcel P; Firmin, David N; Sosnovik, David E. (BioMed Central, 2012)Diffusion Tensor MRI (DTI) of the human heart \(in\) \(vivo\) has to date been performed in 2D and at a single phase of the cardiac cycle. Here we perform 3D tractography of the human heart \(in\) \(vivo\) at both end ... -
Diffusion Tensor Imaging in Patients with Glioblastoma Multiforme Using the Supertoroidal Model
Mekkaoui, Choukri; Metellus, Philippe; Kostis, William J.; Martuzzi, Roberto; Pereira, Fabricio R.; Beregi, Jean-Paul; Reese, Timothy G.; Constable, Todd R.; Jackowski, Marcel P. (Public Library of Science, 2016)Purpose Diffusion Tensor Imaging (DTI) is a powerful imaging technique that has led to improvements in the diagnosis and prognosis of cerebral lesions and neurosurgical guidance for tumor resection. Traditional tensor ... -
Dual-Phase Cardiac Diffusion Tensor Imaging with Strain Correction
Stoeck, Christian T.; Kalinowska, Aleksandra; von Deuster, Constantin; Harmer, Jack; Chan, Rachel W.; Niemann, Markus; Manka, Robert; Atkinson, David; Sosnovik, David E.; Mekkaoui, Choukri; Kozerke, Sebastian (Public Library of Science, 2014)Purpose In this work we present a dual-phase diffusion tensor imaging (DTI) technique that incorporates a correction scheme for the cardiac material strain, based on 3D myocardial tagging. Methods: In vivo dual-phase cardiac ... -
Fiber Architecture in Remodeled Myocardium Revealed with a Quantitative Diffusion CMR Tractography Framework and Histological Validation
Huang, Shuning; Thiagalingam, Aravinda; Jackowski, Marcel P; Mekkaoui, Choukri; Chen, Howard H; Dai, Guangping; Reese, Timothy G.; Kostis, William Jason; Maurovich-Horvat, Pal; Ruskin, Jeremy Neil; Hoffman, Udo; Sosnovik, David E. (BioMed Central, 2012)Background: The study of myofiber reorganization in the remote zone after myocardial infarction has been performed in 2D. Microstructural reorganization in remodeled hearts, however, can only be fully appreciated by ... -
Improving the accuracy of multi breath-hold diffusion tensor MRI tractography of the heart using dynamic motioncorrection
Mekkaoui, Choukri; Nielles-Vallespin, Sonia; Jackowski, Marcel P; Gatehouse, Peter D; Pennell, Dudley J; Firmin, David N; Sosnovik, David E. (BioMed Central, 2013) -
Left Ventricular Remodeling Following Myocardial Infarction Revealed with a Quantitative Diffusion MRI Tractography Framework
Mekkaoui, Choukri; Huang, Shuning; Dai, Guangping; Reese, Timothy G.; Thiagalingam, Aravinda; Maurovich-Horvat, Pal; Ruskin, Jeremy Neil; Hoffmann, Udo; Jackowski, Marcel P; Sosnovik, David E. (BioMed Central, 2012)A cardiac-tailored framework for 3D Diffusion Tensor MRI tractography is developed and used to characterize myofiber architecture in normal and remodeled myocardium. We show that myofibers in the subepicardium of the remote ... -
Myocardial infarct delineation in vivo using diffusion tensor MRI and the tractographic propagation angle
Mekkaoui, Choukri; Huang, Shuning; Dai, Guangping; Reese, Timothy G.; Ruskin, Jeremy Neil; Hoffmann, Udo; Jackowski, Marcel P; Sosnovik, David E. (BioMed Central, 2013)