Now showing items 1-20 of 20

    • The Association between Oxytocin and Social Capital 

      Fujiwara, Takeo; Kubzansky, Laura Diane; Matsumoto, Kenji; Kawachi, Ichiro (Public Library of Science, 2012)
      Background: Oxytocin is known to be related to social behaviors, including trust. However, few studies have investigated the association between oxytocin levels and social capital. Thus, we tested the hypothesis that ...
    • Associations between air pollution and perceived stress: the Veterans Administration Normative Aging Study 

      Mehta, Amar J; Kubzansky, Laura D; Coull, Brent A; Kloog, Itai; Koutrakis, Petros; Sparrow, David; Spiro, Avron; Vokonas, Pantel; Schwartz, Joel (BioMed Central, 2015)
      Background: There is mixed evidence suggesting that air pollution may be associated with increased risk of developing psychiatric disorders. We aimed to investigate the association between air pollution and non-specific ...
    • Associations of Trauma Exposure and Posttraumatic Stress Symptoms With Venous Thromboembolism Over 22 Years in Women 

      Sumner, Jennifer A.; Kubzansky, Laura D.; Kabrhel, Christopher; Roberts, Andrea L.; Chen, Qixuan; Winning, Ashley; Gilsanz, Paola; Rimm, Eric B.; Glymour, Maria M.; Koenen, Karestan C. (John Wiley and Sons Inc., 2016)
      Background: Trauma exposure and posttraumatic stress disorder (PTSD) have been linked to myocardial infarction and stroke in women, with biological and behavioral mechanisms implicated in underlying risk. The third most ...
    • Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes? 

      Cornelis, Marilyn C.; Chiuve, Stephanie E.; Glymour, M. Maria; Chang, Shun-Chiao; Tchetgen Tchetgen, Eric J.; Liang, Liming; Koenen, Karestan C.; Rimm, Eric B.; Kawachi, Ichiro; Kubzansky, Laura D. (Public Library of Science, 2014)
      While research has suggested that being married may confer a health advantage, few studies to date have investigated the role of marital status in the development of type 2 diabetes. We examined whether men who are not ...
    • Education and Coronary Heart Disease Risk 

      Loucks, Eric B.; Gilman, Stephen Edward; Howe, Chanelle J.; Kawachi, Ichiro; Kubzansky, Laura Diane; Rudd, Rima E.; Martin, Laurie T.; Nandi, Arijit; Wilhelm, Aude; Buka, Stephen L. (SAGE Publications, 2014)
      OBJECTIVE Education is inversely associated with coronary heart disease (CHD) risk, however the mechanisms are poorly understood. The study objectives were to evaluate the extent to which rarely measured factors (literacy, ...
    • The Effects of Stress at Work and at Home on Inflammation and Endothelial Dysfunction 

      Non, Amy L.; Rimm, Eric B.; Kawachi, Ichiro; Rewak, Marissa A.; Kubzansky, Laura D. (Public Library of Science, 2014)
      This study examined whether stress at work and at home may be related to dysregulation of inflammation and endothelial function, two important contributors to the development of cardiovascular disease. In order to explore ...
    • A Framework for Examining Social Stress and Susceptibility to Air Pollution in Respiratory Health 

      Clougherty, Jane E.; Kubzansky, Laura Diane (National Institute of Environmental Health Sciences, 2009)
      Objective: There is growing interest in disentangling the health effects of spatially clustered social and physical environmental exposures and in exploring potential synergies among them, with particular attention directed ...
    • Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses 

      Okbay, Aysu; Baselmans, Bart M.L.; De Neve, Jan-Emmanuel; Turley, Patrick; Nivard, Michel G.; Fontana, Mark Alan; Meddens, S. Fleur W.; Linnér, Richard Karlsson; Rietveld, Cornelius A.; Derringer, Jaime; Gratten, Jacob; Lee, James J.; Liu, Jimmy Z.; de Vlaming, Ronald; Ahluwalia, Tarunveer S.; Buchwald, Jadwiga; Cavadino, Alana; Frazier-Wood, Alexis C.; Furlotte, Nicholas A.; Garfield, Victoria; Geisel, Marie Henrike; Gonzalez, Juan R.; Haitjema, Saskia; Karlsson, Robert; van der Laan, Sander W.; Ladwig, Karl-Heinz; Lahti, Jari; van der Lee, Sven J.; Lind, Penelope A.; Liu, Tian; Matteson, Lindsay; Mihailov, Evelin; Miller, Michael B.; Minica, Camelia C.; Nolte, Ilja M.; Mook-Kanamori, Dennis; van der Most, Peter J.; Oldmeadow, Christopher; Qian, Yong; Raitakari, Olli; Rawal, Rajesh; Realo, Anu; Rueedi, Rico; Schmidt, Börge; Smith, Albert V.; Stergiakouli, Evie; Tanaka, Toshiko; Taylor, Kent; Wedenoja, Juho; Wellmann, Juergen; Westra, Harm-Jan; Willems, Sara M.; Zhao, Wei; Amin, Najaf; Bakshi, Andrew; Boyle, Patricia A.; Cherney, Samantha; Cox, Simon R.; Davies, Gail; Davis, Oliver S.P.; Ding, Jun; Direk, Nese; Eibich, Peter; Emeny, Rebecca T.; Fatemifar, Ghazaleh; Faul, Jessica D.; Ferrucci, Luigi; Forstner, Andreas; Gieger, Christian; Gupta, Richa; Harris, Tamara B.; Harris, Juliette M.; Holliday, Elizabeth G.; Hottenga, Jouke-Jan; De Jager, Philip L.; Kaakinen, Marika A.; Kajantie, Eero; Karhunen, Ville; Kolcic, Ivana; Kumari, Meena; Launer, Lenore J.; Franke, Lude; Li-Gao, Ruifang; Koini, Marisa; Loukola, Anu; Marques-Vidal, Pedro; Montgomery, Grant W.; Mosing, Miriam A.; Paternoster, Lavinia; Pattie, Alison; Petrovic, Katja E.; Pulkki-Råback, Laura; Quaye, Lydia; Räikkönen, Katri; Rudan, Igor; Scott, Rodney J.; Smith, Jennifer A.; Sutin, Angelina R.; Trzaskowski, Maciej; Vinkhuyzen, Anna E.; Yu, Lei; Zabaneh, Delilah; Attia, John R.; Bennett, David A.; Berger, Klaus; Bertram, Lars; Boomsma, Dorret I.; Snieder, Harold; Chang, Shun-Chiao; Cucca, Francesco; Deary, Ian J.; van Duijn, Cornelia M.; Eriksson, Johan G.; Bültmann, Ute; de Geus, Eco J.C.; Groenen, Patrick J.F.; Gudnason, Vilmundur; Hansen, Torben; Hartman, Catharine A.; Haworth, Claire M.A.; Hayward, Caroline; Heath, Andrew C.; Hinds, David A.; Hyppönen, Elina; Iacono, William G.; Järvelin, Marjo-Riitta; Jöckel, Karl-Heinz; Kaprio, Jaakko; Kardia, Sharon L.R.; Keltikangas-Järvinen, Liisa; Kraft, Peter; Kubzansky, Laura D.; Lehtimäki, Terho; Magnusson, Patrik K.E.; Martin, Nicholas G.; McGue, Matt; Metspalu, Andres; Mills, Melinda; de Mutsert, Renée; Oldehinkel, Albertine J.; Pasterkamp, Gerard; Pedersen, Nancy L.; Plomin, Robert; Polasek, Ozren; Power, Christine; Rich, Stephen S.; Rosendaal, Frits R.; den Ruijter, Hester M.; Schlessinger, David; Schmidt, Helena; Svento, Rauli; Schmidt, Reinhold; Alizadeh, Behrooz Z.; Sørensen, Thorkild I.A.; Spector, Tim D.; Steptoe, Andrew; Terracciano, Antonio; Thurik, A. Roy; Timpson, Nicholas J.; Tiemeier, Henning; Uitterlinden, André G.; Vollenweider, Peter; Wagner, Gert G.; Weir, David R.; Yang, Jian; Conley, Dalton C.; Smith, George Davey; Hofman, Albert; Johannesson, Magnus; Laibson, David I.; Medland, Sarah E.; Meyer, Michelle N.; Pickrell, Joseph K.; Esko, Tõnu; Krueger, Robert F.; Beauchamp, Jonathan P.; Koellinger, Philipp D.; Benjamin, Daniel J.; Bartels, Meike; Cesarini, David (2016)
      We conducted genome-wide association studies of three phenotypes: subjective well-being (N = 298,420), depressive symptoms (N = 161,460), and neuroticism (N = 170,910). We identified three variants associated with subjective ...
    • Genome-wide polygenic scoring for a 14-year long-term average depression phenotype 

      Chang, Shun-Chiao; Glymour, M Maria; Walter, Stefan; Liang, Liming; Koenen, Karestan C; Tchetgen, Eric J; Cornelis, Marilyn C; Kawachi, Ichiro; Rimm, Eric; Kubzansky, Laura D (Wiley Periodicals, Inc., 2014)
      Background: Despite moderate heritability estimates for depression-related phenotypes, few robust genetic predictors have been identified. Potential explanations for this discrepancy include the use of phenotypic measures ...
    • Health Assets in the Family and Maintaining Optimal Weight Across the Lifespan 

      Chen, Ying (2016-04-25)
      Family health research has been dominated by the deficit-based perspective, which focused on studying the detrimental effects of risky family environment. In comparison, the possible health benefits of positive family ...
    • Lead Concentrations in Relation to Multiple Biomarkers of Cardiovascular Disease: The Normative Aging Study 

      Peters, Junenette L.; Kubzansky, Laura Diane; Ikeda, Ai; Fang, Shona C.; Sparrow, David; Weisskopf, Marc G.; Wright, Robert O.; Vokonas, Pantel S; Hu, Howard; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2012)
      Background: Lead exposure has been associated with cardiovascular disease (CVD) in animal and human studies. However, the mechanisms of action have not been fully elucidated. We therefore examined the relationship between ...
    • Performance of Polygenic Scores for Predicting Phobic Anxiety 

      Walter, Stefan; Glymour, M. Maria; Koenen, Karestan; Liang, Liming; Tchetgen Tchetgen, Eric J.; Cornelis, Marilyn; Chang, Shun-Chiao; Rimm, Eric; Kawachi, Ichiro; Kubzansky, Laura D. (Public Library of Science, 2013)
      Context Anxiety disorders are common, with a lifetime prevalence of 20% in the U.S., and are responsible for substantial burdens of disability, missed work days and health care utilization. To date, no causal genetic ...
    • Protocol for an Experimental Investigation of the Roles of Oxytocin and Social Support in Neuroendocrine, Cardiovascular, and Subjective Responses to Stress across Age and Gender 

      Kubzansky, Laura Diane; Mendes, Wendy B; Appleton, Allison; Block, Jason Perry; Adler, Gail Kurr (BioMed Central, 2009)
      Background: Substantial empirical evidence has demonstrated that individuals who are socially isolated or have few positive social connections seem to age at a faster rate and have more chronic diseases. Oxytocin is a ...
    • Relation of Cumulative Low-Level Lead Exposure to Depressive and Phobic Anxiety Symptom Scores in Middle-Age and Elderly Women 

      Eum, Ki-Do; Korrick, Susan Abigail; Weuve, Jennifer Lynn; Okereke, Olivia Ifeoma; Kubzansky, Laura Diane; Hu, Howard; Weisskopf, Marc G. (National Institute of Environmental Health Sciences, 2012)
      Background: Different lines of evidence suggest that low-level lead exposure could be a modifiable risk factor for adverse psychological symptoms, but little work has explored this relation. Objective: We assessed whether ...
    • Social Integration and Reduced Risk of Coronary Heart Disease in WomenNovelty and Significance 

      Chang, Shun-Chiao; Glymour, Maria Lee; Cornelis, Marilyn; Walter, Stefan; Rimm, Eric Bruce; Tchetgen Tchetgen, Eric Joel; Kawachi, Ichiro; Kubzansky, Laura Diane (Ovid Technologies (Wolters Kluwer Health), 2017)
      RATIONALE: Higher social integration is associated with lower cardiovascular mortality; however, whether it is associated with incident coronary heart disease (CHD), especially in women, and whether associations differ ...
    • Social stressors and air pollution across New York City communities: a spatial approach for assessing correlations among multiple exposures 

      Shmool, Jessie LC; Kubzansky, Laura D; Dotson Newman, Ogonnaya; Spengler, John; Shepard, Peggy; Clougherty, Jane E (BioMed Central, 2014)
      Background: Recent toxicological and epidemiological evidence suggests that chronic psychosocial stress may modify pollution effects on health. Thus, there is increasing interest in refined methods for assessing and ...
    • Socioeconomic and Other Social Stressors and Biomarkers of Cardiometabolic Risk in Youth: A Systematic Review of Less Studied Risk Factors 

      Slopen, Natalie Bea; Goodman, Elizabeth; Koenen, Karestan C.; Kubzansky, Laura Diane (Public Library of Science, 2013)
      Background: Socioeconomic disadvantage and other social stressors in childhood have been linked with cardiometabolic diseases in adulthood; however the mechanisms underlying these observed associations and the timing of ...
    • Stress as a Potential Modifier of the Impact of Lead Levels on Blood Pressure: The Normative Aging Study 

      Peters, Junenette L.; Kubzansky, Laura Diane; McNeely, Eileen; Schwartz, Joel David; Spiro, Avron; Sparrow, David; Wright, Robert O.; Nie, Huiling; Hu, Howard (National Institute of Environmental Health Sciences, 2007)
      Background: Lead exposure and psychological stress have been independently associated with hypertension in various populations, and animal studies suggest that when they co-occur, their effects may be exacerbated. Objectives: ...
    • Synergistic effects of traffic-related air pollution and exposure to violence on urban asthma etiology 

      Clougherty, Jane E.; Levy, Jonathan Ian; Kubzansky, Laura Diane; Ryan, P. Barry; Suglia, Shakira Franco; Canner, Marina Jacobson; Wright, Rosalind Jo (National Institute of Environmental Health Sciences, 2007)
      Background: Disproportionate life stress and consequent physiologic alteration (i.e., immune dysregulation) has been proposed as a major pathway linking socioeconomic position, environmental exposures, and health disparities. ...
    • Unequally Distributed Psychological Assets: Are There Social Disparities in Optimism, Life Satisfaction, and Positive Affect? 

      Boehm, Julia K.; Chen, Ying; Williams, David R.; Ryff, Carol; Kubzansky, Laura D. (Public Library of Science, 2015)
      Socioeconomic status is associated with health disparities, but underlying psychosocial mechanisms have not been fully identified. Dispositional optimism may be a psychosocial process linking socioeconomic status with ...