Now showing items 1-7 of 7

    • Adipokine Hormones and Hand Osteoarthritis: Radiographic Severity and Pain 

      Massengale, Mei; Lu, Bing; Pan, John Jun-Hao; Katz, Jeffrey Neil; Solomon, Daniel Hal (Public Library of Science, 2012)
      Introduction: Obesity's association with hand osteoarthritis cannot be fully explained by mechanical loading. We examined the relationship between adipokines and radiographic hand osteoarthritis severity and pain. Methods: ...
    • Coronal tibial slope is associated with accelerated knee osteoarthritis: data from the Osteoarthritis Initiative 

      Driban, Jeffrey B.; Stout, Alina C.; Duryea, Jeffrey; Lo, Grace H.; Harvey, William F.; Price, Lori Lyn; Ward, Robert J.; Eaton, Charles B.; Barbe, Mary F.; Lu, Bing; McAlindon, Timothy E. (BioMed Central, 2016)
      Background: Accelerated knee osteoarthritis may be a unique subset of knee osteoarthritis, which is associated with greater knee pain and disability. Identifying risk factors for accelerated knee osteoarthritis is vital ...
    • Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals 

      Mercer, Emileigh; Rekedal, Laura; Garg, Rajesh Kumar; Lu, Bing; Massarotti, Elena M.; Solomon, Daniel Hal (BioMed Central, 2012)
      Introduction: Hydroxychloroquine (HCQ) is a common disease modifying therapy for the treatment of rheumatoid arthritis (RA). Prior research suggests that HCQ may reduce the risk of diabetes mellitus in patients with RA. ...
    • A prospective study of impaired fasting glucose and type 2 diabetes in China: The Kailuan study 

      Vaidya, Anand; Cui, Liufu; Sun, Lixia; Lu, Bing; Chen, Shuohua; Liu, Xing; Zhou, Yong; Liu, Xiurong; Xie, Xiaobing; Hu, Frank B.; Wu, Shouling; Gao, Xiang (Wolters Kluwer Health, 2016)
      Abstract The worldwide prevalence and incidence of diabetes and obesity are increasing in pandemic proportions. This is particularly relevant for China, where an extremely large population is growing, aging, and urbanizing. ...
    • PTPN22.6, a Dominant Negative Isoform of PTPN22 and Potential Biomarker of Rheumatoid Arthritis 

      Chang, Hui-Hsin; Tai, Tzong-Shyuan; Lu, Bing; Iannaccone, Christine; Cernadas, Manuela; Weinblatt, Michael Elliott; Shadick, Nancy Ann; Miaw, Shi-Chuen; Ho, I-Cheng (Public Library of Science, 2012)
      PTPN22 is a tyrosine phosphatase and functions as a damper of TCR signals. A C-to-T single nucleotide polymorphism (SNP) located at position 1858 of human PTPN22 cDNA and converting an arginine (R620) to tryptophan (W620) ...
    • Soft drink intake and progression of radiographic knee osteoarthritis: data from the osteoarthritis initiative 

      Lu, Bing; Ahmad, Oneeb; Zhang, Fang-Fang; Driban, Jeffrey B; Duryea, Jeffrey; Lapane, Kate L; McAlindon, Timothy; Eaton, Charles B (BMJ Publishing Group, 2013)
      Objectives: We examine the prospective association of soft drink consumption with radiographic progression of knee osteoarthritis (OA). Design: Prospective cohort study. Setting: This study used data from the osteoarthritis ...
    • Sustained rheumatoid arthritis remission is uncommon in clinical practice 

      Prince, Femke HM; Bykerk, Vivian P; Shadick, Nancy Ann; Lu, Bing; Cui, Jing; Frits, Michelle; Iannaccone, Christine K; Weinblatt, Michael Elliott; Solomon, Daniel Hal (BioMed Central, 2012)
      Introduction: Remission is an important goal of therapy in rheumatoid arthritis (RA), but data on duration of remission are lacking. Our objective was to describe the duration of remission in RA, assessed by different ...