Now showing items 1-4 of 4

    • Global Metabolomic Profiling Reveals an Association of Metal Fume Exposure and Plasma Unsaturated Fatty Acids 

      Wei, Yongyue; Wang, Zhaoxi; Chang, Chiung-yu; Fan, Tianteng; Su, Li; Chen, Feng; Christiani, David C. (Public Library of Science, 2013)
      Background: Welding-associated air pollutants negatively affect the health of exposed workers; however, their molecular mechanisms in causing disease remain largely unclear. Few studies have systematically investigated the ...
    • A Large Scale Gene-Centric Association Study of Lung Function in Newly-Hired Female Cotton Textile Workers with Endotoxin Exposure 

      Zhang, Ruyang; Zhao, Yang; Chu, Minjie; Mehta, Amar Jayant; Wei, Yongyue; Liu, Yao; Xun, Pengcheng; Bai, Jianling; Yu, Hao; Su, Li; Zhang, Hongxi; Hu, Zhibin; Shen, Hongbing; Chen, Feng; Christiani, David C. (Public Library of Science, 2013)
      Background: Occupational exposure to endotoxin is associated with decrements in pulmonary function, but how much variation in this association is explained by genetic variants is not well understood. Objective: We aimed ...
    • Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer 

      Wang, Yufei; McKay, James D; Rafnar, Thorunn; Wang, Zhaoming; Timofeeva, Maria N; Broderick, Peter; Zong, Xuchen; Laplana, Marina; Wei, Yongyue; Han, Younghun; Lloyd, Amy; Delahaye-Sourdeix, Manon; Chubb, Daniel; Gaborieau, Valerie; Wheeler, William; Chatterjee, Nilanjan; Thorleifsson, Gudmar; Sulem, Patrick; Liu, Geoffrey; Kaaks, Rudolf; Henrion, Marc; Kinnersley, Ben; Vallée, Maxime; LeCalvez-Kelm, Florence; Stevens, Victoria L; Gapstur, Susan M; Chen, Wei V; Zaridze, David; Szeszenia-Dabrowska, Neonilia; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Mates, Dana; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Krokan, Hans E; Gabrielsen, Maiken Elvestad; Skorpen, Frank; Vatten, Lars Johan; Njølstad, Inger; Chen, Chu; Goodman, Gary; Benhamou, Simone; Vooder, Tonu; Välk, Kristjan; Nelis, Mari; Metspalu, Andres; Lener, Marcin; Lubiński, Jan; Johansson, Mattias; Vineis, Paolo; Agudo, Antonio; Clavel-Chapelon, Francoise; Bueno-de-Mesquita, H Bas; Trichopoulos, Dimitrios; Khaw, Kay-Tee; Johansson, Mikael; Weiderpass, Elisabete; Tjønneland, Anne; Riboli, Elio; Lathrop, Mark; Scelo, Ghislaine; Albanes, Demetrius; Caporaso, Neil E; Ye, Yuanqing; Gu, Jian; Wu, Xifeng; Spitz, Margaret R; Dienemann, Hendrik; Rosenberger, Albert; Su, Li; Matakidou, Athena; Eisen, Timothy; Stefansson, Kari; Risch, Angela; Chanock, Stephen J; Christiani, David Christopher; Hung, Rayjean J; Brennan, Paul; Landi, Maria Teresa; Houlston, Richard S; Amos, Christopher I (Springer Nature, 2014)
      We conducted imputation to the 1000 Genomes Project of four genome-wide association studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 controls) and genotyped an additional 10,246 cases and ...
    • Thrombocytopenia Is Associated with Acute Respiratory Distress Syndrome Mortality: An International Study 

      Wang, Tiehua; Liu, Zhuang; Wang, Zhaoxi; Duan, Meili; Li, Gang; Wang, Shupeng; Li, Wenxiong; Zhu, Zhaozhong; Wei, Yongyue; Christiani, David C.; Li, Ang; Zhu, Xi (Public Library of Science, 2014)
      Background: Early detection of the Acute Respiratory Distress Syndrome (ARDS) has the potential to improvethe prognosis of critically ill patients admitted to the intensive care unit (ICU). However, no reliable biomarkers ...