Now showing items 1-6 of 6

    • Circulating adiponectin and cardiovascular mortality in patients with type 2 diabetes mellitus: evidence of sexual dimorphism 

      Menzaghi, Claudia; Xu, Min; Salvemini, Lucia; De Bonis, Concetta; Palladino, Giuseppe; Huang, Tao; Copetti, Massimiliano; Zheng, Yan; Li, Yanping; Fini, Grazia; Hu, Frank B; Bacci, Simonetta; Qi, Lu; Trischitta, Vincenzo (BioMed Central, 2014)
      Background: The pathogenesis of cardiovascular (CV) mortality, whose rate is increased in type 2 diabetes, is poorly understood. While high serum adiponectin is associated with increased CV mortality in the general population, ...
    • DNA Methylation Variants at HIF3A Locus, B-Vitamin Intake, and Long-term Weight Change: Gene-Diet Interactions in Two U.S. Cohorts 

      Huang, Tao; Zheng, Yan; Qi, Qibin; Xu, Min; Ley, Sylvia H.; Li, Yanping; Kang, Jae H.; Wiggs, Janey; Pasquale, Louis R.; Chan, Andrew T.; Rimm, Eric B.; Hunter, David J.; Manson, JoAnn E.; Willett, Walter C.; Hu, Frank B.; Qi, Lu (American Diabetes Association, 2015)
      The first epigenome-wide association study of BMI identified DNA methylation at an HIF3A locus associated with BMI. We tested the hypothesis that DNA methylation variants are associated with BMI according to intake of B ...
    • Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta‐Analysis of Randomized Controlled Trials 

      Li, Yanping; Huang, Tianyi; Zheng, Yan; Muka, Tauland; Troup, Jenna; Hu, Frank B. (John Wiley and Sons Inc., 2016)
      Background: Results from observational and genetic epidemiological studies suggest that lower serum homocysteine levels are associated with lower incidence of cardiovascular disease (CVD). Numerous randomized controlled ...
    • Genetic variation of fasting glucose and changes in glycemia in response to 2-year weight-loss diet intervention: the POUNDS Lost trial 

      Wang, Tiange; Huang, Tao; Zheng, Yan; Rood, Jennifer; Bray, George A.; Sacks, Frank M.; Qi, Lu (2016)
      Objective: Weight loss intervention through diet modification has been widely used to improve obesity-related hyperglycemia; however, little is known about whether genetic variation modifies the intervention effect. We ...
    • Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference 

      Wen, Wanqing; Kato, Norihiro; Hwang, Joo-Yeon; Guo, Xingyi; Tabara, Yasuharu; Li, Huaixing; Dorajoo, Rajkumar; Yang, Xiaobo; Tsai, Fuu-Jen; Li, Shengxu; Wu, Ying; Wu, Tangchun; Kim, Soriul; Guo, Xiuqing; Liang, Jun; Shungin, Dmitry; Adair, Linda S.; Akiyama, Koichi; Allison, Matthew; Cai, Qiuyin; Chang, Li-Ching; Chen, Chien-Hsiun; Chen, Yuan-Tsong; Cho, Yoon Shin; Choi, Bo Youl; Gao, Yutang; Go, Min Jin; Gu, Dongfeng; Han, Bok-Ghee; He, Meian; Hixson, James E.; Hu, Yanling; Huang, Tao; Isono, Masato; Jung, Keum Ji; Kang, Daehee; Kim, Young Jin; Kita, Yoshikuni; Lee, Juyoung; Lee, Nanette R.; Lee, Jeannette; Wang, Yiqin; Liu, Jian-Jun; Long, Jirong; Moon, Sanghoon; Nakamura, Yasuyuki; Nakatochi, Masahiro; Ohnaka, Keizo; Rao, Dabeeru; Shi, Jiajun; Sull, Jae Woong; Tan, Aihua; Ueshima, Hirotsugu; Wu, Chen; Xiang, Yong-Bing; Yamamoto, Ken; Yao, Jie; Ye, Xingwang; Yokota, Mitsuhiro; Zhang, Xiaomin; Zheng, Yan; Qi, Lu; Rotter, Jerome I.; Jee, Sun Ha; Lin, Dongxin; Mohlke, Karen L.; He, Jiang; Mo, Zengnan; Wu, Jer-Yuarn; Tai, E. Shyong; Lin, Xu; Miki, Tetsuro; Kim, Bong-Jo; Takeuchi, Fumihiko; Zheng, Wei; Shu, Xiao-Ou (Nature Publishing Group, 2016)
      Sixty genetic loci associated with abdominal obesity, measured by waist circumference (WC) and waist-hip ratio (WHR), have been previously identified, primarily from studies conducted in European-ancestry populations. We ...
    • Metabolites of Glutamate Metabolism Are Associated With Incident Cardiovascular Events in the PREDIMED PREvención con DIeta MEDiterránea (PREDIMED) Trial 

      Zheng, Yan; Hu, Frank B.; Ruiz‐Canela, Miguel; Clish, Clary B.; Dennis, Courtney; Salas‐Salvado, Jordi; Hruby, Adela; Liang, Liming; Toledo, Estefania; Corella, Dolores; Ros, Emilio; Fitó, Montserrat; Gómez‐Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra‐Majem, Lluis; Estruch, Ramón; Martínez‐González, Miguel A. (John Wiley and Sons Inc., 2016)
      Background: Glutamate metabolism may play a role in the pathophysiology of cardiometabolic disorders. However, there is limited evidence of an association between glutamate‐related metabolites and, moreover, changes in ...