Browsing by Author "Kim, Jae Hun"

Now showing items 1-5 of 5

    • Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma 

      Overby, Darryl R.; Zhou, Enhua; Vargas-Pinto, Rocio; Pedrigi, Ryan M.; Fuchshofer, Rudolf; Braakman, Sietse T.; Gupta, Ritika; Perkumas, Kristin M.; Sherwood, Joseph M.; Vahabikashi, Amir; Dang, Quynh Nhu; Kim, Jae Hun; Ethier, C. Ross; Stamer, W. Daniel; Fredberg, Jeffrey J.; Johnson, Mark (Proceedings of the National Academy of Sciences, 2014)
      Increased flow resistance is responsible for the elevated intraocular pressure characteristic of glaucoma, but the cause of this resistance increase is not known. We tested the hypothesis that altered biomechanical behavior ...

    • Geometric constraints during epithelial jamming 

      Atia, Lior Nisim; Bi, Dapeng; Sharma, Yasha; Mitchel, Jennifer; Gweon, Bomi; Koehler, Stephan A.; DeCamp, Stephen; Lan, Bo; Kim, Jae Hun; Hirsch, Rebecca; Pegoraro, Adrian; Lee, Kyu Ha; Starr, Jacqueline Rose; Weitz, David A.; Martin, Adam; Park, Jin-Ah; Butler, James P.; Fredberg, Jeffrey J. (Springer Science and Business Media LLC, 2018-04-02)

    • Monolayer Stress Microscopy: Limitations, Artifacts, and Accuracy of Recovered Intercellular Stresses 

      Tambe, Dhananjay T; Croutelle, Ugo; Trepat, Xavier; Park, Chan Young Young; Kim, Jae Hun; Millet, Emil J.; Butler, James Preston; Fredberg, Jeffrey J. (Public Library of Science, 2013)
      In wound healing, tissue growth, and certain cancers, the epithelial or the endothelial monolayer sheet expands. Within the expanding monolayer sheet, migration of the individual cell is strongly guided by physical forces ...

    • Propulsion and navigation within the advancing monolayer sheet 

      Kim, Jae Hun; Serra-Picamal, Xavier; Tambe, Dhananjay; Zhou, Enhua; Park, Chan Young Young; Sadati, Monirosadat; Park, Jin-Ah; Krishnan, Ramaswamy; Gweon, Bomi; Millet, Emil; Butler, James P.; Trepat, Xavier; Fredberg, Jeffrey J. (Springer Nature, 2013)
      As a wound heals, or a body plan forms, or a tumour invades, observed cellular motions within the advancing cell swarm are thought to stem from yet to be observed physical stresses that act in some direct and causal ...

    • Unjamming and cell shape in the asthmatic airway epithelium 

      Park, Jin-Ah; Kim, Jae Hun; Bi, Dapeng; Mitchel, Jennifer; Qazvini, Nader Taheri; Tantisira, Kelan; Park, Chan Young Young; McGill, Maureen P; Kim, Sae-Hoon; Gweon, Bomi; Notbohm, Jacob K; Steward Jr, Robert; Burger, Stephanie; Randell, Scott H.; Kho, Alvin Thong-Juak; Tambe, Dhananjay; Hardin, Corey; Shore, Stephanie Ann; Israel, Elliot; Weitz, David A.; Tschumperlin, Daniel; Henske, Elizabeth Petri; Weiss, Scott Tillman; Manning, Mary Ellen; Butler, James P.; Drazen, Jeffrey Mark; Fredberg, Jeffrey J. (Nature Publishing Group, 2015)
      From coffee beans flowing in a chute to cells remodelling in a living tissue, a wide variety of close-packed collective systems— both inert and living—have the potential to jam. The collective can sometimes flow like a ...