Now showing items 1-20 of 42

    • Acclimatization across space and time in the effects of temperature on mortality: a time-series analysis 

      Lee, Mihye; Nordio, Francesco; Zanobetti, Antonella; Kinney, Patrick; Vautard, Robert; Schwartz, Joel (BioMed Central, 2014)
      Background: Climate change has increased the days of unseasonal temperature. Although many studies have examined the association between temperature and mortality, few have examined the timing of exposure where whether ...
    • Acute and Chronic Effects of Particles on Hospital Admissions in New England 

      Coull, Brent Andrew; Zanobetti, Antonella; Koutrakis, Petros; Schwartz, Joel David (Public Library of Science, 2012)
      Background: Many studies have reported significant associations between exposure to \(PM_{2.5}\) and hospital admissions, but all have focused on the effects of short-term exposure. In addition all these studies have relied ...
    • Air conditioning and source-specific particles as modifiers of the effect of PM(10) on hospital admissions for heart and lung disease. 

      Janssen, Nicole A H; Schwartz, Joel David; Zanobetti, Antonella; Suh MacIntosh, Helen H. (National Institute of Environmental Health Sciences, 2002)
      Studies on acute effects of particulate matter (PM) air pollution show significant variability in exposure-effect relations among cities. Recent studies have shown an influence of ventilation on personal/indoor-outdoor ...
    • Air Pollution and ST-Segment Depression in Elderly Subjects 

      MacCallum, Gail; Canner, Marina J.; Gold, Diane R.; Litonjua, Augusto Ampil; Zanobetti, Antonella; Coull, Brent Andrew; Schwartz, Joel David; Verrier, Richard Leonard; Nearing, Bruce David; Suh MacIntosh, Helen H.; Stone, Peter Howard (National Institue of Environmental Health Sciences, 2005)
      Increased levels of daily ambient particle pollution have been associated with increased risk of cardiovascular morbidity. Black carbon (BC) is a measure of the traffic-related component of particles. We investigated ...
    • Air Pollution Exposure and Abnormal Glucose Tolerance during Pregnancy: The Project Viva Cohort 

      Fleisch, Abby F.; Gold, Diane R.; Rifas-Shiman, Sheryl L.; Koutrakis, Petros; Schwartz, Joel D.; Kloog, Itai; Melly, Steven; Coull, Brent A.; Zanobetti, Antonella; Gillman, Matthew W.; Oken, Emily (National Institute of Environmental Health Sciences, 2014)
      Background: Exposure to fine particulate matter (PM with diameter ≤ 2.5 μm; PM2.5) has been linked to type 2 diabetes mellitus, but associations with hyperglycemia in pregnancy have not been well studied. Methods: We studied ...
    • Air Pollution, Aeroallergens, and Emergency Room Visits for Acute Respiratory Diseases and Gastroenteric Disorders among Young Children in Six Italian Cities 

      Orazzo, Flavia; Nespoli, Luigi; Ito, Kazuhiko; Tassinari, Davide; Giardina, Daniela; Funis, Maurizio; Cecchi, Alessandra; Trapani, Chiara; Forgeschi, Gisella; Vignini, Massimo; Nosetti, Luana; Pigna, Sabrina; Zanobetti, Antonella (National Institute of Environmental Health Sciences, 2009)
      Background: Past studies reported evidence of associations between air pollution and respiratory symptoms and morbidity for children. Few studies examined associations between air pollution and emergency room (ER) visits ...
    • Air Pollution, Smoking, and Plasma Homocysteine 

      Baccarelli, Andrea; Zanobetti, Antonella; Martinelli, Ida; Grillo, Paolo; Hou, Lifang; Lanzani, Guido; Mannucci, Pier Mannuccio; Bertazzi, Pier Alberto; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2006)
      Background: Mild hyperhomocysteinemia is independently associated with an increased risk of cardiovascular disease. Air pollution exposure induces short-term inflammatory changes that may determine hyperhomocysteinemia, ...
    • Alu and LINE-1 methylation and lung function in the normative ageing study 

      Lange, Nancy E; Sordillo, Joanne; Tarantini, Letizia; Bollati, Valentina; Sparrow, David; Vokonas, Pantel; Zanobetti, Antonella; Schwartz, Joel David; Baccarelli, Andrea; Litonjua, Augusto Ampil; Demeo, Dawn Lisa (BMJ Publishing Group, 2012)
      Objectives: To investigate the association between methylation of transposable elements Alu and long-interspersed nuclear elements (LINE-1) and lung function. Design: Cohort study. Setting: Outpatient Veterans Administration ...
    • Ambient air pollution, lung function, and airway responsiveness in asthmatic children 

      Ierodiakonou, Despo; Zanobetti, Antonella; Coull, Brent Andrew; Melly, Steven John; Postma, Dirkje S.; Boezen, H. Marike; Vonk, Judith M.; Williams, Paul V.; Shapiro, Gail G.; McKone, Edward F.; Hallstrand, Teal S.; Koenig, Jane Q.; Schildcrout, Jonathan S.; Lumley, Thomas; Fuhlbrigge, Anne Louise; Koutrakis, Petros; Schwartz, Joel David; Weiss, Scott Tillman; Gold, Diane R. (Elsevier BV, 2016)
      Background: Although ambient air pollution has been linked to reduced lung function in healthy children, longitudinal analyses of pollution effects in asthma are lacking. Objective: To investigate pollution effects in ...
    • Associations between Changes in City and Address Specific Temperature and QT Interval - The VA Normative Aging Study 

      Mehta, Amar J.; Kloog, Itai; Zanobetti, Antonella; Coull, Brent A.; Sparrow, David; Vokonas, Pantel; Schwartz, Joel (Public Library of Science, 2014)
      Background: The underlying mechanisms of the association between ambient temperature and cardiovascular morbidity and mortality are not well understood, particularly for daily temperature variability. We evaluated if daily ...
    • Associations between outdoor temperature and markers of inflammation: a cohort study 

      Halonen, Jaana I; Zanobetti, Antonella; Sparrow, David; Vokonas, Pantel S; Schwartz, Joel David (BioMed Central, 2010)
      Background: Associations between ambient temperature and cardiovascular mortality are well established. This study investigated whether inflammation could be part of the mechanism leading to temperature-related cardiovascular ...
    • Associations of Fine Particulate Matter Species with Mortality in the United States: A Multicity Time-Series Analysis 

      Dai, Lingzhen; Zanobetti, Antonella; Koutrakis, Petros; Schwartz, Joel D. (NLM-Export, 2014)
      Background: Epidemiological studies have examined the association between PM2.5 and mortality, but uncertainty remains about the seasonal variations in PM2.5-related effects and the relative importance of species. Objectives: ...
    • Baseline Repeated Measures from Controlled Human Exposure Studies: Associations between Ambient Air Pollution Exposure and the Systemic Inflammatory Biomarkers IL-6 and Fibrinogen 

      Thompson, Aaron M.S.; Zanobetti, Antonella; Silverman, Frances; Schwartz, Joel David; Coull, Brent Andrew; Urch, Bruce; Speck, Mary; Brook, Jeffrey R.; Manno, Michael; Gold, Diane R. (National Institute of Environmental Health Sciences, 2009)
      Introduction: Systemic inflammation may be one of the mechanisms mediating the association between ambient air pollution and cardiovascular morbidity and mortality. Interleukin-6 (IL-6) and fibrinogen are biomarkers of ...
    • Brachial Artery Responses to Ambient Pollution, Temperature, and Humidity in People with Type 2 Diabetes: A Repeated-Measures Study 

      Zanobetti, Antonella; Luttmann-Gibson, Heike; Horton, Edward S.; Cohen, Allison; Coull, Brent A.; Hoffmann, Barbara; Schwartz, Joel D.; Mittleman, Murray A.; Li, Yongsheng; Stone, Peter H.; de Souza, Celine; Lamparello, Brooke; Koutrakis, Petros; Gold, Diane R. (National Institute of Environmental Health Sciences, 2014)
      Background: Extreme weather and air pollution are associated with increased cardiovascular risk in people with diabetes. Objectives: In a population with diabetes, we conducted a novel assessment of vascular brachial artery ...
    • Cardiac Autonomic Dysfunction: Particulate Air Pollution Effects Are Modulated by Epigenetic Immunoregulation of Toll‐like Receptor 2 and Dietary Flavonoid Intake 

      Zhong, Jia; Colicino, Elena; Lin, Xinyi; Mehta, Amar; Kloog, Itai; Zanobetti, Antonella; Byun, Hyang‐Min; Bind, Marie‐Abèle; Cantone, Laura; Prada, Diddier; Tarantini, Letizia; Trevisi, Letizia; Sparrow, David; Vokonas, Pantel; Schwartz, Joel; Baccarelli, Andrea A. (Blackwell Publishing Ltd, 2015)
      Background: Short‐term fine particles (PM2.5) exposure is associated with reduced heart rate variability, a strong predictor of cardiac mortality among older people. Identifying modifiable factors that confer susceptibility ...
    • Chronic effects of temperature on mortality in the Southeastern USA using satellite-based exposure metrics 

      Shi, Liuhua; Liu, Pengfei; Wang, Yan; Zanobetti, Antonella; Kosheleva, Anna; Koutrakis, Petros; Schwartz, Joel (Nature Publishing Group, 2016)
      Climate change may affect human health, particularly for elderly individuals who are vulnerable to temperature changes. While many studies have investigated the acute effects of heat, only a few have dealt with the chronic ...
    • The Concentration-Response Relation Between PM\(_{2.5}\) and Daily Deaths. 

      Schwartz, Joel David; Laden, Francine; Zanobetti, Antonella (National Institute of Environmental Health Sciences, 2002)
      Particulate air pollution at commonly occurring concentrations is associated with daily deaths. Recent attention has focused on the shape of the concentration-response curve, particularly at low doses. Several recent ...
    • The Effect of Particulate Air Pollution on Emergency Admissions for Myocardial Infarction: A Multicity Case-Crossover Analysis 

      Zanobetti, Antonella; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2005)
      Recently, attention has focused on whether particulate air pollution is a specific trigger of myocardial infarction (MI). The results of several studies of single locations assessing the effects of ambient particular matter ...
    • The effect of primary organic particles on emergency hospital admissions among the elderly in 3 US cities 

      Kioumourtzoglou, Marianthi-Anna; Zanobetti, Antonella; Schwartz, Joel D; Coull, Brent A; Dominici, Francesca; Suh, Helen H (BioMed Central, 2013)
      Background: Fine particle (PM2.5) pollution related to combustion sources has been linked to a variety of adverse health outcomes. Although poorly understood, it is possible that organic carbon (OC) species, particularly ...
    • The effect of weather on respiratory and cardiovascular deaths in 12 U.S. cities. 

      Braga, Alfésio L F; Zanobetti, Antonella; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2002)
      We carried out time-series analyses in 12 U.S. cities to estimate both the acute effects and the lagged influence of weather on respiratory and cardiovascular disease (CVD) deaths. We fit generalized additive Poisson ...