Now showing items 1-9 of 9

    • Does the Mechanism of Lymph Node Invasion Affect Survival in Patients with Pancreatic Ductal Adenocarcinoma? 

      Konstantinidis, Ioannis T; Deshpande, Vikram; Hui, Hui; Wargo, Jennifer Ann; Fernandez-Del Castillo, Carlos F.; Thayer, Sarah P.; Androutsopoulos, Vasiliki; Lauwers, Gregory Y.; Warshaw, Andrew Louis; Ferrone, Cristina Rosa (Springer Science + Business Media, 2010)
      Background: Lymph node metastases are prognostically significant in pancreatic ductal adenocarcinoma. Little is known about the significance of direct lymph node invasion. Aim: The aim of this study is to find out whether ...
    • Evolving Patterns in the Detection and Outcomes of Pancreatic Neuroendocrine Neoplasms 

      Vagefi, Parsia A.; Razo, Oswaldo; Deshpande, , Vikram; McGrath, Deborah J.; Lauwers, Gregory Y.; Thayer, Sarah P.; Warshaw, Andrew Louis; Fernandez-del Castilllo, Carlos (American Medical Association (AMA), 2007)
      Objective: To assess changing patterns in the detection and outcomes of pancreatic neuroendocrine neoplasms (PNENs). Design: Retrospective review from May 21, 1977, through September 16, 2005. Setting: Massachusetts General ...
    • Gallbladder Lesions Identified on Ultrasound. Lessons from the Last 10 Years 

      Konstantinidis, Ioannis T; Bajpai, Surabhi; Kambadakone, Avinash R.; Tanabe, Kenneth Kenji; Berger, David Lawrence; Hui, Hui; Sahani, Dushyant V.; Lauwers, Gregory Y.; Fernandez-Del Castillo, Carlos F.; Warshaw, Andrew Louis; Ferrone, Cristina Rosa (Springer Nature, 2011)
      Background: Possible mass lesions identified on ultrasound (US) of the gallbladder may prompt an aggressive surgical intervention due to the possibility of a malignant neoplasm. Aim: This study aims to utilize a large ...
    • Global Genomic Analysis of Intraductal Papillary Mucinous Neoplasms of the Pancreas Reveals Significant Molecular Differences Compared to Ductal Adenocarcinoma 

      Fritz, Stefan; Fernandez-Del Castillo, Carlos F.; Mino-Kenudson, Mari; Crippa, Stefano; Deshpande, Vikram; Lauwers, Gregory Y.; Warshaw, Andrew Louis; Thayer, Sarah P.; Iafrate, Anthony John (Ovid Technologies (Wolters Kluwer Health), 2009)
      Objective: To determine whether intraductal papillary mucinous neoplasms of the pancreas (IPMNs) have a different genetic background compared with ductal adenocarcinoma (PDAC). Summary Background Data: The biologic and ...
    • Mucin-Producing Neoplasms of the Pancreas: An Analysis of Distinguishing Clinical and Epidemiologic Characteristics 

      Crippa, Stefano; Fernández–del Castillo, Carlos; Salvia, Roberto; Finkelstein, Dianne Madelyn; Bassi, Claudio; Domínguez, Ismael; Muzikansky, Alona; Thayer, Sarah P.; Falconi, Massimo; Mino–Kenudson, Mari; Capelli, Paola; Lauwers, Gregory Y.; Partelli, Stefano; Pederzoli, Paolo; Warshaw, Andrew Louis (Elsevier BV, 2010)
      Background & Aims: Mucin-producing neoplasms (MPNs) of the pancreas include mucinous cystic neoplasms (MCNs) and main-duct, branch-duct, and combined intraductal papillary mucinous neoplasms (IPMNs). MCNs and branch-duct ...
    • Mucinous Cystic Neoplasm of the Pancreas is Not an Aggressive Entity 

      Crippa, Stefano; Salvia, Roberto; Warshaw, Andrew Louis; Domínguez, Ismael; Bassi, Claudio; Falconi, Massimo; Thayer, Sarah P.; Zamboni, Giuseppe; Lauwers, Gregory Y.; Mino-Kenudson, Mari; Capelli, Paola; Pederzoli, Paolo; Castillo, Carlos Fernández-del (Ovid Technologies (Wolters Kluwer Health), 2008)
      Objective: Mucinous cystic neoplasms (MCNs) of the pancreas have often been confused with intraductal papillary mucinous neoplasms. We evaluated the clinicopathologic characteristics, prevalence of cancer, and prognosis ...
    • Pancreatic Duct Glands Are Distinct Ductal Compartments That React to Chronic Injury and Mediate Shh-Induced Metaplasia 

      Strobel, Oliver; Rosow, David E.; Rakhlin, Elena Y.; Lauwers, Gregory Y.; Trainor, Amanda G.; Alsina, Janivette; Fernández–Del Castillo, Carlos; Warshaw, Andrew Louis; Thayer, Sarah P. (Elsevier BV, 2010)
      BACKGROUND & AIMS: Pancreatic intraepithelial neoplasia (PanIN) are pancreatic cancer precursor lesions of unclear origin and significance. PanIN aberrantly express sonic hedgehog (Shh), an initiator of pancreatic cancer, ...
    • Pancreatic Ductal Adenocarcinoma 

      Konstantinidis, Ioannis T; Warshaw, Andrew Louis; Allen, Jill; Blaszkowsky, Lawrence Scott; Castillo, Carlos; Deshpande, Vikram; Hong, Theodore Sunki; Kwak, Eunice Lee; Lauwers, Gregory Y.; Ryan, David P.; Wargo, Jennifer Ann; Lillemoe, Keith Douglas; Ferrone, Cristina Rosa (Ovid Technologies (Wolters Kluwer Health), 2013)
      Objective: Patients who undergo an R0 resection of their pancreatic ductal adenocarcinoma (PDAC) have an improved survival compared with patients who undergo an R1 resection. It is unclear whether an R1 resection confers ...
    • Pancreatic Ductal Adenocarcinoma: Long-Term Survival Does Not Equal Cure 

      Ferrone, Cristina Rosa; Pieretti-Vanmarcke, Rafael; Bloom, Jordan P; Hui, Hui; Szymonifka, Jackye; Wargo, Jennifer Ann; Thayer, Sarah P.; Lauwers, Gregory Y.; Deshpande, Vikram; Mino-Kenudson, Mari; Fernandez-Del Castillo, Carlos F.; Lillemoe, Keith Douglas; Warshaw, Andrew Louis (Elsevier BV, 2012)
      Background: Pancreatic ductal adenocarcinoma represents 90% of pancreatic cancers and is an important cause of cancer death in the United States. Operative resection remains as the only treatment providing prolonged survival, ...