Now showing items 1-3 of 3

    • Augmented Pulmonary Responses to Acute Ozone Exposure in Obese Mice: Roles of TNFR2 and IL-13 

      Williams, Alison Suzanne; Mathews, Joel Andrew; Kasahara, David Itiro; Chen, Lucas; Wurmbrand, Allison Patricia; Si, Huiqing; Shore, Stephanie Ann (National Institute of Environmental Health Sciences, 2013)
      Background: Acute ozone (O3) exposure results in greater inflammation and airway hyperresponsiveness (AHR) in obese versus lean mice. Objectives: We examined the hypothesis that these augmented responses to O3 are the ...
    • Impact of Adiponectin Overexpression on Allergic Airways Responses in Mice 

      Verbout, Norah G.; Benedito, Leandro; Williams, Alison S.; Kasahara, David I.; Wurmbrand, Allison P.; Si, Huiqing; Halayko, Andrew J.; Hug, Christopher; Shore, Stephanie A. (Hindawi Publishing Corporation, 2013)
      Obesity is an important risk factor for asthma. Obese individuals have decreased circulating adiponectin, an adipose-derived hormone with anti-inflammatory properties. We hypothesized that transgenic overexpression of ...
    • Role of the Adiponectin Binding Protein, T-Cadherin (Cdh13), in Allergic Airways Responses in Mice 

      Williams, Alison S.; Kasahara, David I.; Verbout, Norah G.; Fedulov, Alexey V.; Zhu, Ming; Si, Huiqing; Wurmbrand, Allison Patricia; Hug, Christopher; Ranscht, Barbara; Shore, Stephanie Ann (Public Library of Science, 2012)
      Adiponectin is an adipose derived hormone that declines in obesity. We have previously shown that exogenous administration of adiponectin reduces allergic airways responses in mice. T-cadherin (T-cad; Cdh13) is a binding ...