Browsing by Author "Lele, Pushkar Prakash"
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Dynamics of Mechanosensing in the Bacterial Flagellar Motor
Lele, Pushkar Prakash; Hosu, Basarab Gabriel; Berg, Howard Curtis (Proceedings of the National Academy of Sciences, 2013)Mechanosensing by flagella is thought to trigger bacterial swarmer-cell differentiation, an important step in pathogenesis. How flagellar motors sense mechanical stimuli is not known. To study this problem, we suddenly ... -
FRAP Analysis: Accounting for Bleaching during Image Capture
Wu, Jun; Shekhar, Nandini; Lele, Pushkar Prakash; Lele, Tanmay P. (Public Library of Science, 2012)The analysis of Fluorescence Recovery After Photobleaching (FRAP) experiments involves mathematical modeling of the fluorescence recovery process. An important feature of FRAP experiments that tends to be ignored in the ... -
A Rotary Motor Drives Flavobacterium Gliding
Shrivastava, Abhishek; Lele, Pushkar Prakash; Berg, Howard Curtis (Elsevier BV, 2015)Cells of Flavobacterium johnsoniae, a rod-shaped bacterium devoid of pili or flagella, glide over glass at speeds of 2–4 μm/s [ 1 ]. Gliding is powered by a protonmotive force [ 2 ], but the machinery required for this ...