Browsing by Author "Kim, Hye-Jung"

Now showing items 1-3 of 3

    • Mechanism of EBV Inducing Anti-Tumour Immunity and Its Therapeutic Use 

      Choi, Il-Kyu; Wang, Zhe; Ke, Qiang; Hong, Min; Paul, Dereck W.; Fernandes, Stacey M.; Hu, Zhuting; Stevens, Jonathan; Guleria, Indira; Kim, Hye-Jung; Cantor, Harvey; Wucherpfennig, Kai; Brown, Jennifer R.; Ritz, Jerome; Zhang, Baochun (Springer Science and Business Media LLC, 2020-12-23)
      Tumour-associated antigens (TAAs) comprise a large collection of non-mutated cellular antigens recognized by T cells in human and murine cancers. Their potential as immunotherapy targets has been explored for over two ...

    • Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes 

      Kreslavsky, Taras; Kim, Hye-Jung; Koralov, Sergei B.; Ghitza, Dvora; Buch, Thorsten; Cantor, Harvey; Rajewsky, Klaus; von Boehmer, Harald (The Rockefeller University Press, 2013)
      Antigen receptor editing—a process of secondary rearrangements of antigen receptor genes in autoreactive lymphocytes—is a well-established tolerance mechanism in B cells, whereas its role in T cells remains controversial. ...

    • Retinoic Acid Can Enhance Conversion of Naive into Regulatory T Cells Independently of Secreted Cytokines 

      Nolting, Jens; Reuter, Sabine; Stuelten, Christina; Li, Peng; Sucov, Henry; Kim, Byung-Gyu; Letterio, John J.; Kretschmer, Karsten; Daniel, Carolin; Kim, Hye-Jung; von Boehmer, Harald (The Rockefeller University Press, 2009)
      It has been reported that retinoic acid (RA) enhances regulatory T (T reg) cell conversion by inhibiting the secretion of cytokines that interfere with conversion. This report shows that these conclusions provide a partial ...