Browsing by Author "Mansour, Michael"

Now showing items 1-3 of 3

    • Dectin-1 Activation Controls Maturation of β-1,3-Glucan-containing Phagosomes 

      Mansour, Michael Karim; Tam, Jenny M.; Khan, Nida S.; Seward, Michael; Davids, Peter J.; Puranam, Sravanthi; Sokolovska, Anna; Sykes, David Brian; Dagher, Zeina; Becker, Christine; Tanne, Antoine; Reedy, Jennifer L; Stuart, Lynda M.; Vyas, Jatin Mahesh (American Society for Biochemistry & Molecular Biology (ASBMB), 2013)
      Background: Dectin-1 is able to recognize and phagocytose the fungal carbohydrate, β-1,3-glucan, but its contribution to phagosomal maturation has not been explored. Results: Dectin-1-dependent Syk activation promotes ...

    • HIV-Care Outcome in Saudi Arabia; a Longitudinal Cohort 

      Al-Mozaini, Maha A.; Mansour, Michael K.; Al-Hokail, Abdullah A.; Mohmed, Magid A.; Daham, Munirah A. Bin; Al-Abdely, Hail M.; Frayha, Husn H.; Al-Rabiah, Fahad A.; Alhajjar, Sami H.; Keshavjee, Salmaan; Adra, Chaker N.; Alrajhi, Abdulrahman A. (2014)
      Background: Clinical characteristics of HIV-1 infection in people inhabiting Western, Sub-Saharan African, and South-East Asian countries are well recognized. However, very little information is available with regard to ...

    • Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin 

      Palchaudhuri, Rahul; Saez, Borja; Hoggatt, Jonathan George; Schajnovitz, Amir; Sykes, David Brian; Tate, Tiffany A; Czechowicz, Agnieszka; Kfoury, Youmna Sami; Ruchika, FNU; Rossi, Derrick J; Verdine, Gregory L.; Mansour, Michael Karim; Scadden, David Thomas (Springer Nature, 2016)
      Hematopoietic stem cell transplantation (HSCT) offers curative therapy for patients with hemoglobinopathies, congenital immunodeficiencies, and other conditions, possibly including AIDS. Autologous HSCT using genetically ...