Now showing items 1-7 of 7

    • Core-Shell Nanostars for Multimodal Therapy and Imaging 

      Li, Mengyuan; Li, Lele; Zhan, Changyou; Kohane, Daniel S. (Ivyspring International Publisher, 2016)
      The coupling of diagnostic capability and effective therapy in a single multifunctional nanomedicine is desirable but remains challenging. Here, we developed multifunctional nanoparticles consisting of a gold nanostar ...
    • Drug delivery, biomaterials and nanomedicine: an interview with Daniel S Kohane 

      Kohane, Daniel S (Future Science Ltd, 2016)
      Daniel Kohane speaks to Francesca Lake, Managing Editor: Obtaining his MD and PhD in Physiology from Boston University (MA, USA), Dan Kohane went on to complete residencies in Pediatrics at Boston Children’s Hospital (MA, ...
    • Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles 

      Zaman, Paula; Wang, Julia; Blau, Adam; Wang, Weiping; Li, Tina; Kohane, Daniel S; Loscalzo, Joseph; Zhang, Ying-Yi (Dove Medical Press, 2016)
      Incorporation of proteins into dextran sulfate (DS)-chitosan (CS) nanoparticles (DSCS NPs) is commonly performed using entrapment procedures, in which protein molecules are mixed with DS and CS until particle formation ...
    • Macroporous Nanowire Nanoelectronic Scaffolds for Synthetic Tissues 

      Tian, Bozhi; Liu, Jia; Dvir, Tal; Jin, Lihua; Tsui, Jonathan H.; Qing, Quan; Suo, Zhigang; Langer, Robert S.; Kohane, Daniel Solomon; Lieber, Charles M. (Nature Publishing Group, 2012)
      The development of three-dimensional (3D) synthetic biomaterials as structural and bioactive scaffolds is central to fields ranging from cellular biophysics to regenerative medicine. As of yet, these scaffolds cannot ...
    • Nanowired three-dimensional cardiac patches 

      Dvir, Tal; Timko, Brian Paul; Brigham, Mark Daniel; Naik, Shreesh R.; Karajanagi, Sandeep Sidram; Levy, Oren; Jin, Hongwei; Parker, Kevin Kit; Langer, Robert S.; Kohane, Daniel Solomon (Springer Nature, 2011)
      Engineered cardiac patches for treating damaged heart tissues after a heart attack are normally produced by seeding heart cells within three-dimensional porous biomaterial scaffolds. These biomaterials, which are usually ...
    • Photoswitchable Nanoparticles for Triggered Tissue Penetration and Drug Delivery 

      Tong, Rong; Hemmati, Houman D.; Langer, Robert S.; Kohane, Daniel Solomon (American Chemical Society, 2012)
      We report a novel nanoparticulate drug delivery system that undergoes reversible volume change from 150 to 40 nm upon phototriggering with UV light. The volume change of these monodisperse nanoparticles comprising spiropyran, ...
    • Titanium Coating of the Boston Keratoprosthesis 

      Salvador-Culla, Borja; Jeong, Kyung Jae; Kolovou, Paraskevi Evi; Chiang, Homer H.; Chodosh, James; Dohlman, Claes H.; Kohane, Daniel S. (The Association for Research in Vision and Ophthalmology, 2016)
      Purpose We tested the feasibility of using titanium to enhance adhesion of the Boston Keratoprosthesis (B-KPro), ultimately to decrease the risk of implant-associated complications. Methods: Cylindrical rods were made of ...