Browsing by Author "Thayer, Sarah P."

Now showing items 1-7 of 7

    • Does the Mechanism of Lymph Node Invasion Affect Survival in Patients with Pancreatic Ductal Adenocarcinoma? 

      Konstantinidis, Ioannis T; Deshpande, Vikram; Hui, Hui; Wargo, Jennifer Ann; Fernandez-Del Castillo, Carlos F.; Thayer, Sarah P.; Androutsopoulos, Vasiliki; Lauwers, Gregory Y.; Warshaw, Andrew Louis; Ferrone, Cristina Rosa (Springer Science + Business Media, 2010)
      Background: Lymph node metastases are prognostically significant in pancreatic ductal adenocarcinoma. Little is known about the significance of direct lymph node invasion. Aim: The aim of this study is to find out whether ...

    • Evolving Patterns in the Detection and Outcomes of Pancreatic Neuroendocrine Neoplasms 

      Vagefi, Parsia A.; Razo, Oswaldo; Deshpande, , Vikram; McGrath, Deborah J.; Lauwers, Gregory Y.; Thayer, Sarah P.; Warshaw, Andrew Louis; Fernandez-del Castilllo, Carlos (American Medical Association (AMA), 2007)
      Objective: To assess changing patterns in the detection and outcomes of pancreatic neuroendocrine neoplasms (PNENs). Design: Retrospective review from May 21, 1977, through September 16, 2005. Setting: Massachusetts General ...

    • Global Genomic Analysis of Intraductal Papillary Mucinous Neoplasms of the Pancreas Reveals Significant Molecular Differences Compared to Ductal Adenocarcinoma 

      Fritz, Stefan; Fernandez-Del Castillo, Carlos F.; Mino-Kenudson, Mari; Crippa, Stefano; Deshpande, Vikram; Lauwers, Gregory Y.; Warshaw, Andrew Louis; Thayer, Sarah P.; Iafrate, Anthony John (Ovid Technologies (Wolters Kluwer Health), 2009)
      Objective: To determine whether intraductal papillary mucinous neoplasms of the pancreas (IPMNs) have a different genetic background compared with ductal adenocarcinoma (PDAC). Summary Background Data: The biologic and ...

    • Mucin-Producing Neoplasms of the Pancreas: An Analysis of Distinguishing Clinical and Epidemiologic Characteristics 

      Crippa, Stefano; Fernández–del Castillo, Carlos; Salvia, Roberto; Finkelstein, Dianne Madelyn; Bassi, Claudio; Domínguez, Ismael; Muzikansky, Alona; Thayer, Sarah P.; Falconi, Massimo; Mino–Kenudson, Mari; Capelli, Paola; Lauwers, Gregory Y.; Partelli, Stefano; Pederzoli, Paolo; Warshaw, Andrew Louis (Elsevier BV, 2010)
      Background & Aims: Mucin-producing neoplasms (MPNs) of the pancreas include mucinous cystic neoplasms (MCNs) and main-duct, branch-duct, and combined intraductal papillary mucinous neoplasms (IPMNs). MCNs and branch-duct ...

    • Mucinous Cystic Neoplasm of the Pancreas is Not an Aggressive Entity 

      Crippa, Stefano; Salvia, Roberto; Warshaw, Andrew Louis; Domínguez, Ismael; Bassi, Claudio; Falconi, Massimo; Thayer, Sarah P.; Zamboni, Giuseppe; Lauwers, Gregory Y.; Mino-Kenudson, Mari; Capelli, Paola; Pederzoli, Paolo; Castillo, Carlos Fernández-del (Ovid Technologies (Wolters Kluwer Health), 2008)
      Objective: Mucinous cystic neoplasms (MCNs) of the pancreas have often been confused with intraductal papillary mucinous neoplasms. We evaluated the clinicopathologic characteristics, prevalence of cancer, and prognosis ...

    • Pancreatic Duct Glands Are Distinct Ductal Compartments That React to Chronic Injury and Mediate Shh-Induced Metaplasia 

      Strobel, Oliver; Rosow, David E.; Rakhlin, Elena Y.; Lauwers, Gregory Y.; Trainor, Amanda G.; Alsina, Janivette; Fernández–Del Castillo, Carlos; Warshaw, Andrew Louis; Thayer, Sarah P. (Elsevier BV, 2010)
      BACKGROUND & AIMS: Pancreatic intraepithelial neoplasia (PanIN) are pancreatic cancer precursor lesions of unclear origin and significance. PanIN aberrantly express sonic hedgehog (Shh), an initiator of pancreatic cancer, ...

    • Pancreatic Ductal Adenocarcinoma: Long-Term Survival Does Not Equal Cure 

      Ferrone, Cristina Rosa; Pieretti-Vanmarcke, Rafael; Bloom, Jordan P; Hui, Hui; Szymonifka, Jackye; Wargo, Jennifer Ann; Thayer, Sarah P.; Lauwers, Gregory Y.; Deshpande, Vikram; Mino-Kenudson, Mari; Fernandez-Del Castillo, Carlos F.; Lillemoe, Keith Douglas; Warshaw, Andrew Louis (Elsevier BV, 2012)
      Background: Pancreatic ductal adenocarcinoma represents 90% of pancreatic cancers and is an important cause of cancer death in the United States. Operative resection remains as the only treatment providing prolonged survival, ...