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    • RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer 

      Chimge, Nyam-Osor; Little, Gillian H.; Baniwal, Sanjeev K.; Adisetiyo, Helty; Xie, Ying; Zhang, Tian; O'Laughlin, Andie; Liu, Zhi Y.; Ulrich, Peaches; Martin, Anthony; Mhawech-Fauceglia, Paulette; Ellis, Matthew J.; Tripathy, Debu; Groshen, Susan; Liang, Chengyu; Li, Zhe; Schones, Dustin E.; Frenkel, Baruch (Nature Publishing Group, 2016)
      Recent high-throughput studies revealed recurrent RUNX1 mutations in breast cancer, specifically in oestrogen receptor-positive (ER+) tumours. However, mechanisms underlying the implied RUNX1-mediated tumour suppression ...