Now showing items 1-1 of 1

    • Amyloid-β Protein Protects Against Microbial Infection In Transgenic C. elegans and 5XFAD Mice 

      Kumar, Deepak; Choi, Se Hoon; Washicosky, Kevin J.; Eimer, William; Tucker, Stephanie Catherine; Ghofrani, Jessica; Lefkowitz, Aaron; McColl, Gawain; Goldstein, Lee E.; Tanzi, Rudolph Emile; Moir, Robert D. (American Association for the Advancement of Science (AAAS), 2016)
      The amyloid-β peptide (Aβ) is a key protein in Alzheimer's disease (AD) pathology. We previously reported in vitro evidence suggesting Aβ is an antimicrobial peptide. Here we provide the first in vivo evidence showing high ...