Browsing by Author "Deaton, Aimee"
Now showing items 1-3 of 3
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Multiplexed Illumina sequencing libraries from picogram quantities of DNA
Bowman, Sarah K; Simon, Matthew D; Deaton, Aimee M; Tolstorukov, Michael; Borowsky, Mark L; Kingston, Robert E (BioMed Central, 2013)Background: High throughput sequencing is frequently used to discover the location of regulatory interactions on chromatin. However, techniques that enrich DNA where regulatory activity takes place, such as chromatin ... -
Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming
West, Jason A.; Cook, April; Alver, Burak H.; Stadtfeld, Matthias; Deaton, Aimee; Hochedlinger, Konrad; Park, Peter J.; Tolstorukov, Michael Y.; Kingston, Robert E. (2014)Chromatin structure determines DNA accessibility. We compare nucleosome occupancy in mouse and human embryonic stem cells (ESCs), induced-pluripotent stem cells (iPSCs), and differentiated cell types using MNase-seq. To ... -
The structure of Polycomb-repressed chromatin in the bithorax complex
Bowman, Sarah K.; Deaton, Aimee Marianne; Domingues, Heber; Bender, Welcome W.; Kingston, Robert Edward (BioMed Central, 2013)