Now showing items 1-2 of 2

    • Identifying Mechanisms of Apoptotic Pore Formation With Programmatic Ensemble Modeling 

      Bachman, John (2016-02-05)
      Mitochondrial outer membrane permeabilization is a key step in the apoptotic cell death program, regulating life-death decisions in response to cytotoxic drugs and other forms of cell stress. In this thesis I use mathematical ...
    • Programming biological models in Python using PySB 

      Lopez, Carlos Francisco; Muhlich, Jeremy; Bachman, John Ata; Sorger, Peter Karl (Nature Publishing Group, 2013)
      Mathematical equations are fundamental to modeling biological networks, but as networks get large and revisions frequent, it becomes difficult to manage equations directly or to combine previously developed models. Multiple ...