Browsing by Author "Williamson, Kaylyn"

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Identification of promoter targets of enhancers by epigenetic knockdown using TAL DNA binding proteins

Mendenhall, Eric M; Williamson, Kaylyn Elise; Reyon, Deepak; Joung, Jae Keith; Bernstein, Bradley E. (BioMed Central, 2013)
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma

Drier, Yotam; Cotton, Matthew J.; Williamson, Kaylyn E.; Gillespie, Shawn M.; Ryan, Russell J.H.; Kluk, Michael J.; Carey, Christopher D.; Rodig, Scott J.; Sholl, Lynette M; Afrogheh, Amir H.; Faquin, William C.; Queimado, Lurdes; Qi, Jun; Wick, Michael J.; El-Naggar, Adel K.; Bradner, James E.; Moskaluk, Christopher A.; Aster, Jon C.; Knoechel, Birgit; Bernstein, Bradley E. (2016)

Translocation events are frequent in cancer and may create chimeric fusions or ‘regulatory rearrangements’ that drive oncogene overexpression. Here we identify super-enhancer translocations that drive overexpression of the ...