Browsing by Author "Maeda, Takahiro"

Now showing items 1-3 of 3

    • BCL11A Enhancer Dissection by Cas9-Mediated in Situ Saturating Mutagenesis 

      Canver, Matthew Charles; Smith, Elenoe; Pinello, Luca; Sanjana, Neville E.; Shalem, Ophir; Chen, Diane; Schupp, Patrick G.; Vinjamur, Divya S.; Garcia, Sara P.; Luc, Sidinh; Kurita, Ryo; Fujiwara, Yuko; Maeda, Takahiro; Yuan, Guo-Cheng; Zhang, Feng; Orkin, Stuart Holland; Bauer, Daniel Evan; Nakamura, Yukio (Nature, 2015-09-16)

    • Notch signal strength controls cell fate in the haemogenic endothelium 

      Gama-Norton, Leonor; Ferrando, Eva; Ruiz-Herguido, Cristina; Liu, Zenhy; Guiu, Jordi; Islam, Abul B. M. M. K.; Lee, Sung-Uk; Yan, Minhong; Guidos, Cynthia J.; López-Bigas, Nuria; Maeda, Takahiro; Espinosa, Lluis; Kopan, Raphael; Bigas, Anna (Nature Pub. Group, 2015)
      Acquisition of the arterial and haemogenic endothelium fates concurrently occur in the aorta–gonad–mesonephros (AGM) region prior to haematopoietic stem cell (HSC) generation. The arterial programme depends on Dll4 and the ...

    • Snx3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation 

      Chen, Caiyong; Garcia-Santos, Daniel; Ishikawa, Yuichi; Seguin, Alexandra; Li, Liangtao; Fegan, Katherine H.; Hildick-Smith, Gordon J.; Shah, Darshan Anil; Cooney, James A.; Chen, Wen; King, Michael; Yien, Yvette Yee; Schultz, Iman J.; Anderson, Heidi; Dalton, Abigail Goodnow; Freedman, Matthew Lawrence; Kingsley, Paul D.; Palis, James; Hattangadi, Shilpa M.; Lodish, Harvey F.; Ward, Daniel Alexander; Kaplan, Jerry B.; Maeda, Takahiro; Ponka, Prem; Paw, Barry Htin (Elsevier BV, 2013)
      Sorting of endocytic ligands and receptors is critical for diverse cellular processes. The physiological significance of endosomal sorting proteins in vertebrates, however, remains largely unknown. Here we report that ...