Now showing items 1-11 of 11

    • Complex shapes self-assembled from single-stranded DNA tiles 

      Wei, Bryan; Dai, Mingjie; Yin, Peng (Springer Nature, 2012)
      Programmed self-assembly of strands of nucleic acid has proved highly effective for creating a wide range of structures with desired shapes. A particularly successful implementation is DNA origami, in which a long scaffold ...
    • Design and synthesis of dynamically assembling DNA nanostructures 

      Sadowski, John Paul (2014-02-25)
      Kinetically controlled isothermal growth is fundamental to biological development, but it remains challenging to rationally design molecular systems that self-assemble isothermally into complex geometries via prescribed ...
    • Developmental Self-Assembly of a DNA Tetrahedron 

      Sadowski, John P.; Calvert, Colby R.; Zhang, David Yu; Pierce, Niles A.; Yin, Peng (American Chemical Society, 2014)
      Kinetically controlled isothermal growth is fundamental to biological development, yet it remains challenging to rationally design molecular systems that self-assemble isothermally into complex geometries via prescribed ...
    • DNA Brick Crystals with Prescribed Depth 

      Ke, Yonggang; Ong, Luvena L.; Sun, Wei; Song, Jie; Dong, Mingdong; Shih, William M.; Yin, Peng (2014)
      We describe a general framework for constructing two-dimensional crystals with prescribed depth and sophisticated three-dimensional features. These crystals may serve as scaffolds for the precise spatial arrangements of ...
    • DNA directed self-assembly of shape-controlled hydrogels 

      Qi, Hao; Ghodousi, Majid; Du, Yanan; Grun, Casey; Bae, Hojae; Yin, Peng; Khademhosseini, Ali (2013)
      Using DNA as programmable, sequence specific ‘glues’, shape-controlled hydrogel units are self-assembled into prescribed structures. Here we report that aggregates are produced using hydrogel cubes with edge length ranging ...
    • DyNAMiC Workbench: an integrated development environment for dynamic DNA nanotechnology 

      Grun, Casey; Werfel, Justin; Zhang, David Yu; Yin, Peng (The Royal Society, 2015)
      Dynamic DNA nanotechnology provides a promising avenue for implementing sophisticated assembly processes, mechanical behaviours, sensing and computation at the nanoscale. However, design of these systems is complex and ...
    • Genetic encoding of DNA nanostructures and their self-assembly in living bacteria 

      Elbaz, Johann; Yin, Peng; Voigt, Christopher A. (Nature Publishing Group, 2016)
      The field of DNA nanotechnology has harnessed the programmability of DNA base pairing to direct single-stranded DNAs (ssDNAs) to assemble into desired 3D structures. Here, we show the ability to express ssDNAs in Escherichia ...
    • Metallized DNA nanolithography for encoding and transferring spatial information for graphene patterning 

      Jin, Zhong; Sun, Wei; Ke, Yonggang; Shih, Chih-Jen; Paulus, Geraldine Laura Caroline; Hua Wang, Qing; Mu, Bin; Yin, Peng; Strano, Michael S. (Springer Nature, 2013)
      The vision for graphene and other two-dimensional electronics is the direct production of nanoelectronic circuits and barrier materials from a single precursor sheet. DNA origami and single-stranded tiles are powerful ...
    • Optical visualisation of individual biomolecules in densely packed clusters 

      Dai, Mingjie; Jungmann, Ralf; Yin, Peng (2016)
      Recent advances in fluorescence super-resolution microscopy have allowed sub-cellular features and synthetic nanostructures down to ~15 nm in size to be imaged. However, direct optical observation of individual molecular ...
    • Quantitative Super-Resolution Imaging with qPAINT using Transient Binding Analysis 

      Jungmann, Ralf; Avendaño, Maier S; Dai, Mingjie; Woehrstein, Johannes B; Agasti, Sarit S; Feiger, Zachary; Rodal, Avital; Yin, Peng (2016)
      Current super-resolution techniques offer unprecedented spatial resolution, but quantitative counting of spatially unresolvable molecules remains challenging. Here, we use the programmable and specific binding of dye-labeled ...
    • Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes 

      Beliveau, Brian J.; Boettiger, Alistair N.; Avendaño, Maier S.; Jungmann, Ralf; McCole, Ruth B.; Joyce, Eric F.; Kim-Kiselak, Caroline; Bantignies, Frédéric; Fonseka, Chamith Y.; Erceg, Jelena; Hannan, Mohammed A.; Hoang, Hien G.; Colognori, David; Lee, Jeannie T.; Shih, William M.; Yin, Peng; Zhuang, Xiaowei; Wu, Chao-ting (Nature Pub. Group, 2015)
      Fluorescence in situ hybridization (FISH) is a powerful single-cell technique for studying nuclear structure and organization. Here we report two advances in FISH-based imaging. We first describe the in situ visualization ...