Browsing by Author "Pan, Junhua"

Now showing items 1-2 of 2

    • Structural Basis for Continued Antibody Evasion by the SARS-CoV-2 Receptor-Binding Domain 

      Nabel, Katherine G.; Clark, Sarah A.; Shankar, Sundaresh; Pan, Junhua; Clark, Lars; Yang, Pan; Coscia, Adrian; McKay, Lindsay G.A.; Varnum, Haley; Brusic, Vesna; Tolan, Nicole V.; Zhou, Guohai; Desjardins, Michaël; Turbett, Sarah E.; Kanjilal, Sanjat; Sherman, Amy; Dighe, Anand; LaRocque, Regina C.; Ryan, Edward; Tylek, Casey; Cohen-Solal, Joel F.; Darcy, Andhao T.; Tavella, Davide; Clabbers, Anca; Fan, Yao; Griffiths, Anthony; Correia, Ivan R.; Seagal, Jane; Baden, Lindsey; Charles, Richelle; Abraham, Jonathan (2021-12-02)
      Many studies have examined the impact of SARS-CoV-2 variants on neutralizing antibody activity after they have become dominant strains. Here, we evaluate the consequences of further viral evolution. We demonstrate mechanisms ...

    • Structure of the Human Metapneumovirus Polymerase Phosphoprotein Complex 

      Pan, Junhua; Qian, Xinlei; Lattmann, Simon; Sahili, Abbas El; Yeo, Tiong Han; Jia, Huan; Cressey, Tessa; Ludeke, Barbara; Noton, Sarah; Kalocsay, Marian; Fearns, Rachel; Lescar, Julien; Lescar (Nature Publishing Group, 2020-01-09)
      Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) cause severe respiratory diseases in infants and elder adults. Neither a vaccine nor an effective antiviral therapy exists to control RSV or HMPV infections. ...