Browsing by Author "Nairz, Manfred"
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Lp-PLA 2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative MacrophagesCLINICAL PERSPECTIVE
He, Shun; Chousterman, Benjamin; Fenn, Ashley Margaret; Anzai, Atsushi; Nairz, Manfred; Brandt, Martin; Hilgendorf, Ingo; Sun, Yuan; Ye, Yu-Xiang; Iwamoto, Yoshiko; Tricot, Benoit; Weissleder, Ralph; Macphee, Colin; Libby, Peter; Nahrendorf, Matthias; Swirski, Filip K. (Ovid Technologies (Wolters Kluwer Health), 2015)Background—Healing after myocardial infarction (MI) involves the biphasic accumulation of inflammatory Ly-6Chigh and reparative Ly-6Clow monocytes/macrophages. Excessive inflammation disrupts the balance between the 2 ... -
Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages
He, Shun; Chousterman, Benjamin G.; Fenn, Ashley; Anzai, Atsushi; Nairz, Manfred; Brandt, Martin; Hilgendorf, Ingo; Sun, Yuan; Ye, Yu-Xiang; Iwamoto, Yoshiko; Tricot, Benoit; Weissleder, Ralph; Macphee, Colin; Libby, Peter; Nahrendorf, Matthias; Swirski, Filip K. (Lippincott Williams & Wilkins, 2015)Background— Healing after myocardial infarction (MI) involves the biphasic accumulation of inflammatory Ly-6Chigh and reparative Ly-6Clow monocytes/macrophages. Excessive inflammation disrupts the balance between the 2 ... -
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver
Theurl, Igor; Hilgendorf, Ingo; Nairz, Manfred; Tymoszuk, Piotr; Haschka, David; Asshoff, Malte; He, Shun; Gerhardt, Louisa M. S.; Holderried, Tobias A. W.; Seifert, Markus; Sopper, Sieghart; Fenn, Ashley M.; Anzai, Atsushi; Rattik, Sara; McAlpine, Cameron; Theurl, Milan; Wieghofer, Peter; Iwamoto, Yoshiko; Weber, Georg F.; Harder, Nina K.; Chousterman, Benjamin G.; Arvedson, Tara L.; McKee, Mary; Wang, Fudi; Lutz, Oliver M. D.; Rezoagli, Emanuele; Babitt, Jodie L.; Berra, Lorenzo; Prinz, Marco; Nahrendorf, Matthias; Weiss, Guenter; Weissleder, Ralph; Lin, Herbert Y.; Swirski, Filip K. (2016)Iron is an essential component of the erythrocyte protein hemoglobin and is crucial to oxygen transport in vertebrates. In the steady state, erythrocyte production is in equilibrium with erythrocyte removal1. In various ...