Browsing by Author "Gaudin, Raphaël"
Now showing items 1-4 of 4
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Asymmetric formation of coated pits on dorsal and ventral surfaces at the leading edges of motile cells and on protrusions of immobile cells
Kural, Comert; Akatay, Ahmet Ata; Gaudin, Raphaël; Chen, Bi-Chang; Legant, Wesley R.; Betzig, Eric; Kirchhausen, Tom (The American Society for Cell Biology, 2015)Clathrin/AP2-coated vesicles are the principal endocytic carriers originating at the plasma membrane. In the experiments reported here, we used spinning-disk confocal and lattice light-sheet microscopy to study the assembly ... -
Dynamin recruitment and membrane scission at the neck of a clathrin-coated pit
Cocucci, Emanuele; Gaudin, Raphaël; Kirchhausen, Tom (The American Society for Cell Biology, 2014)Dynamin, the GTPase required for clathrin-mediated endocytosis, is recruited to clathrin-coated pits in two sequential phases. The first is associated with coated pit maturation; the second, with fission of the membrane ... -
Sorting of small infectious virus particles by flow virometry reveals distinct infectivity profiles
Gaudin, Raphaël; Barteneva, Natasha S. (2014)The nature and concentration of lipids and proteins at the surface of viruses are essential parameters for determining particle infectiveness. Historically, averaged bulk analysis of viral particles has been the primary ... -
Superinfection exclusion is absent during acute Junin virus infection of Vero and A549 cells
Gaudin, Raphaël; Kirchhausen, Tomas (Nature Publishing Group, 2015)Many viruses have evolved strategies of so-called “superinfection exclusion” to prevent re-infection of a cell that the same virus has already infected. Although Old World arenavirus infection results in down-regulation ...