Now showing items 1-3 of 3

    • The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice 

      Warfield, Kelly L.; Barnard, Dale L.; Enterlein, Sven G.; Smee, Donald F.; Khaliq, Mansoora; Sampath, Aruna; Callahan, Michael V.; Ramstedt, Urban; Day, Craig W. (MDPI, 2016)
      Iminosugars that are competitive inhibitors of endoplasmic reticulum (ER) α-glucosidases have been demonstrated to have antiviral activity against a diverse set of viruses. A novel iminosugar, UV-4B, has recently been shown ...
    • Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome 

      Klase, Zachary A.; Khakhina, Svetlana; Schneider, Adriano De Bernardi; Callahan, Michael V.; Glasspool-Malone, Jill; Malone, Robert (Public Library of Science, 2016)
      The ongoing Zika virus epidemic in the Americas and the observed association with both fetal abnormalities (primary microcephaly) and adult autoimmune pathology (Guillain–Barré syndrome) has brought attention to this ...
    • Zika Virus: Medical Countermeasure Development Challenges 

      Malone, Robert W.; Homan, Jane; Callahan, Michael V.; Glasspool-Malone, Jill; Damodaran, Lambodhar; Schneider, Adriano De Bernardi; Zimler, Rebecca; Talton, James; Cobb, Ronald R.; Ruzic, Ivan; Smith-Gagen, Julie; Janies, Daniel; Wilson, James (Public Library of Science, 2016)
      Introduction: Reports of high rates of primary microcephaly and Guillain–Barré syndrome associated with Zika virus infection in French Polynesia and Brazil have raised concerns that the virus circulating in these regions ...