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    • HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response 

      Chusri, Pattranuch; Kumthip, Kattareeya; Hong, Jian; Zhu, Chuanlong; Duan, Xiaoqiong; Jilg, Nikolaus; Fusco, Dahlene N.; Brisac, Cynthia; Schaefer, Esperance A.; Cai, Dachuan; Peng, Lee F.; Maneekarn, Niwat; Lin, Wenyu; Chung, Raymond T. (Nature Publishing Group, 2016)
      HCV replication disrupts normal endoplasmic reticulum (ER) function and activates a signaling network called the unfolded protein response (UPR). UPR is directed by three ER transmembrane proteins including ATF6, IRE1, and ...
    • A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models 

      Ding, Qiurong; Lee, Youn-Kyoung; Schaefer, Esperance Anne Kreek; Peters, Derek Tilghman; Veres, Adrian; Kim, Kevin; Kuperwasser, Nicolas; Motola, Daniel L; Meissner, Torsten B; Hendriks, William; Trevisan, Marta; Gupta, Rajat; Moisan, Annie; Banks, Eric; Friesen, Max; Schinzel, Robert T.; Xia, Fang; Tang, Alexander; Xia, Yulei; Figueroa, Emmanuel; Wann, Amy; Ahfeldt, Tim; Daheron, Laurence Marie; Zhang, Feng; Rubin, Lee; Peng, Lee F; Chung, Raymond Taeyong; Musunuru, Kiran; Cowan, Chad A. (Elsevier BV, 2013)
      Transcription activator-like effector nucleases (TALENs) are a new class of engineered nucleases that are easier to design to cleave at desired sites in a genome than previous types of nucleases. We report here the use of ...