Browsing by Author "Yu, Wei-Ming"

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A Gata3–Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing

Yu, Wei-Ming; Appler, Jessica M; Kim, Ye-Hyun; Nishitani, Allison M; Holt, Jeffrey R; Goodrich, Lisa V (eLife Sciences Publications, Ltd, 2013)

Information flow through neural circuits is determined by the nature of the synapses linking the subtypes of neurons. How neurons acquire features distinct to each synapse remains unknown. We show that the transcription ...
In Vivo Analysis of Lrig Genes Reveals Redundant and Independent Functions in the Inner Ear

del Rio, Tony; Nishitani, Allison M.; Yu, Wei-Ming; Goodrich, Lisa V. (Public Library of Science, 2013)

Lrig proteins are conserved transmembrane proteins that modulate a variety of signaling pathways from worm to humans. In mammals, there are three family members – Lrig1, Lrig2, and Lrig3 – that are defined by closely related ...